Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28321488 | 0.98 | PTPN22 (0.58) | PTPN22POLBHSD17B10CYP1A2USP2 | |
| SCHEMBL25221463 | 0.80 | ALOX5 (0.48) | PTPN22POLBHSD17B10CYP1A2USP2 | |
| SCHEMBL28013806 | 0.80 | HPRT1 (0.52) | PTPN22POLBHSD17B10CYP1A2USP2 | |
| 1-Naphthol SCHEMBL27453648 | 0.77 | CYP1A2 (0.65) | PTPN22POLBHSD17B10CYP1A2USP2 | |
| SCHEMBL24519126 | 0.77 | NPC1 (0.47) | PTPN22POLBHSD17B10CYP1A2USP2 | |
| SCHEMBL29027 | 0.75 | PTPN22 (0.65) | PTPN22POLBHSD17B10CYP1A2USP2 | |
| SCHEMBL29613822 | 0.75 | PTPN22 (1.00) | PTPN22POLBHSD17B10CYP1A2USP2 | |
| Hydrochloric Acid SCHEMBL28347175 | 0.75 | PTPN22 (1.00) | PTPN22POLBHSD17B10CYP1A2USP2 | |
| SCHEMBL29362162 | 0.75 | PTPN22 (0.65) | PTPN22POLBHSD17B10CYP1A2USP2 | |
| SCHEMBL28483 | 0.75 | PTPN22 (1.00) | PTPN22POLBHSD17B10CYP1A2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106748604-B | Method for synthesizing mono-iodo aromatic hydrocarbon or di-iodo aromatic hydrocarbon based on decarboxylation of aromatic carboxylic acid | 湘潭大学 | 2020-06-05 | — | — | CN | claimed |
| CN-119662037-A | Preparation method of blue dye | 沈阳化工研究院有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20240025872-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LT MATERIALS CO., LTD. (KR) | 2024-01-25 | — | — | US | disclosed |
| US-20240025872-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LT MATERIALS CO., LTD. (KR) | 2024-01-25 | — | — | US | disclosed |
| CN-117327110-A | Compound taking boron as center and naphthofuran as framework and electroluminescent device | 蒲城欧得新材料有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-116988078-A | Metal catalyzed asymmetric coupling method promoted by electrochemical reduction | 中国科学院上海有机化学研究所 | 2023-11-03 | — | — | CN | disclosed |
| EP-4249478-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LT Materials Co., Ltd. (KR) | 2023-09-27 | — | — | EP | disclosed |
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |
| CN-113563399-B | Method for preparing tiacumicin B iodide and other aromatic iodination products and application thereof | 中国科学院南海海洋研究所 | 2023-06-27 | — | — | CN | disclosed |
| US-20230176481-A1 | FILM-FORMING COMPOSITION | NISSAN CHEMICAL CORPORATION (JP) | 2023-06-08 | — | — | US | disclosed |
| US-7919154-B2 | 1-(trifluoromethyl)naphthalene derivative | DIC CORPORATION (JP) | 2011-04-05 | — | — | US | disclosed |
| US-20100140547-A1 | 1-(TRIFLUOROMETHYL)NAPHTHALENE DERIVATIVE | DIC CORPORATION (JP) | 2010-06-10 | — | — | US | disclosed |
| US-20080275253-A1 | halogenation with a halogen donor selected from N-bromosuccinimide, N-iodosuccinimide, N-chlorosuccinimide and N-fluorobenzene-sulfonimide, 1,3-dibromo-5,5-dimethyl imidazolidine-2,4-dione in presence of ZrCl4; bromination of tetramethylsilane | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-11-06 | — | — | US | disclosed |
| US-20080275253-A1 | halogenation with a halogen donor selected from N-bromosuccinimide, N-iodosuccinimide, N-chlorosuccinimide and N-fluorobenzene-sulfonimide, 1,3-dibromo-5,5-dimethyl imidazolidine-2,4-dione in presence of ZrCl4; bromination of tetramethylsilane | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-11-06 | — | — | US | disclosed |
| EP-0443533-A2 | Positive photoresist composition | FUJI PHOTO FILM CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4374262-A | Preparation of hydroxy aromatic carboxylic acids and ester derivatives thereof | CELANESE CORPORATION (US) | 1983-02-15 | — | — | US | disclosed |
| EP-0049616-A1 | Preparation of hydroxy aromatic carboxylic acids and ester derivatives thereof | CELANESE CORPORATION (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4111962-A | Certain substituted 2-phenylnaphtho[1,2-b]furane and -[2,1-b]furane | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-3994968-A | 2-(5'-Halo-6'-methoxynaphth-2'-yl)-acrylic acid | SYNTEX CORPORATION (PM) | 1976-11-30 | — | — | US | disclosed |
| US-3960957-A | 2-(6'-methoxynaphth-2'yl) propionaldoxime and 5'-halo derivatives thereof | SYNTEX CORPORATION (PM) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100140547-A1 | 1-(TRIFLUOROMETHYL)NAPHTHALENE DERIVATIVE | HVCN1, VIM, NES | PTPN22 1662/4885POLB 2640/4885HSD17B10 1350/4885 |
| US-20080275253-A1 | halogenation with a halogen donor selected from N-bromosuccinimide, N-iodosuccinimide, N-chlorosuccinimide and N-fluorobenzene-sulfonimide, 1,3-dibromo-5,5-dimethyl imidazolidine-2,4-dione in presence of ZrCl4; bromination of tetramethylsilane | HDHD5, ZRANB2, CLIC4 | PTPN22 3622/4885POLB 3359/4885HSD17B10 2996/4885 |
| US-20240025872-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, CYP1B1, CYP1A1 | PTPN22 4546/4885POLB 3272/4885HSD17B10 1018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.