Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16023925 | 0.88 | NPBWR1 (0.40) | P2RX7NPBWR1P2RX3PDE10AMCHR1 | |
| SCHEMBL16014856 | 0.86 | P2RX7 (0.44) | P2RX7NPBWR1SMN1; SMN2KDRP2RX3 | |
| SCHEMBL16014805 | 0.85 | P2RX7 (0.43) | P2RX7NPBWR1KDRP2RX3MCHR1 | |
| SCHEMBL16014593 | 0.84 | P2RX7 (0.42) | P2RX7NPBWR1KDRP2RX3MCHR1 | |
| SCHEMBL16014705 | 0.84 | P2RX7 (0.47) | P2RX7NPBWR1P2RX3BUB1MEN1 | |
| SCHEMBL16014562 | 0.82 | P2RX7 (0.41) | P2RX7NPBWR1KDRP2RX3PDE10A | |
| SCHEMBL16014715 | 0.80 | P2RX7 (0.42) | P2RX7NPBWR1P2RX3MCHR1 | |
| SCHEMBL16023894 | 0.77 | SMN1; SMN2 (0.38) | P2RX7NPBWR1SMN1; SMN2PDE10A | |
| SCHEMBL16014359 | 0.75 | P2RX7 (0.41) | P2RX7NPBWR1SMN1; SMN2KDRP2RX3 | |
| SCHEMBL16014845 | 0.74 | ALDH1A1 (0.41) | NPBWR1SMN1; SMN2MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014135472-A1 | ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-09-12 | — | — | WO | disclosed |