Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 10/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16023924 | 0.88 | P2RX7 (0.41) | NPBWR1P2RX7P2RX3MCHR1HTT | |
| SCHEMBL16014642 | 0.86 | NPBWR1 (0.42) | NPBWR1P2RX7P2RX3MCHR1DCTPP1 | |
| SCHEMBL16014737 | 0.81 | NPBWR1 (0.41) | NPBWR1P2RX7P2RX3MCHR1 | |
| SCHEMBL16014625 | 0.78 | P2RX7 (0.48) | NPBWR1P2RX7MCHR1 | |
| SCHEMBL16014593 | 0.77 | P2RX7 (0.42) | NPBWR1P2RX7P2RX3MCHR1DCTPP1 | |
| SCHEMBL16014845 | 0.76 | ALDH1A1 (0.41) | NPBWR1HTT | |
| SCHEMBL16014856 | 0.74 | P2RX7 (0.44) | NPBWR1P2RX7P2RX3MCHR1DCTPP1 | |
| SCHEMBL16014805 | 0.73 | P2RX7 (0.43) | NPBWR1P2RX7P2RX3MCHR1DCTPP1 | |
| SCHEMBL16014359 | 0.73 | P2RX7 (0.41) | NPBWR1P2RX7P2RX3MCHR1DCTPP1 | |
| SCHEMBL16014705 | 0.72 | P2RX7 (0.47) | NPBWR1P2RX7P2RX3BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014135472-A1 | ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-09-12 | — | — | WO | disclosed |