Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10016587 | 0.85 | USP2 (0.55) | POLBNPSR1ALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL5992323 | 0.70 | USP2 (0.49) | POLBNPSR1KMT2AALDH1A1USP2 | |
| SCHEMBL4080674 | 0.68 | USP2 (0.65) | NPSR1GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL3323416 | 0.67 | ALDH1A1 (0.59) | POLBNPSR1ALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL16026437 | 0.67 | ALDH1A1 (0.83) | POLBNPSR1GAAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11816036 | 0.67 | POLB (0.83) | POLBNPSR1GAAKMT2AALDH1A1 | |
| SCHEMBL12593269 | 0.67 | SMN1; SMN2 (0.68) | POLBNPSR1GAAKMT2AALDH1A1 | |
| SCHEMBL13612640 | 0.66 | ALDH1A1 (0.72) | POLBNPSR1KMT2AALDH1A1GLA | |
| SCHEMBL14350981 | 0.66 | NPSR1 (0.69) | POLBNPSR1KMT2AALDH1A1MEN1 | |
| SCHEMBL13804475 | 0.64 | ALDH1A1 (0.71) | POLBNPSR1GAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140255386-A1 | MICRORNA MODULATORS AND METHOD FOR IDENTIFYING AND USING THE SAME | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140255386-A1 | MICRORNA MODULATORS AND METHOD FOR IDENTIFYING AND USING THE SAME | AGO2, RNASE1, TRDMT1 | POLB 2386/4885NPSR1 3040/4885GAA 1241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.