Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159985 | 0.94 | PYGL (0.38) | PYGLKDM4EALDH1A1USP2HPGD | |
| SCHEMBL158941 | 0.87 | KDM4E (0.32) | PYGLKDM4EALDH1A1USP2HPGD | |
| SCHEMBL12302083 | 0.87 | KDM4E (0.33) | PYGLKDM4EALDH1A1USP2HPGD | |
| SCHEMBL175762 | 0.84 | NOTUM (0.40) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL159682 | 0.82 | ALDH1A1 (0.34) | PYGLKDM4EALDH1A1USP2HPGD | |
| SCHEMBL10179271 | 0.81 | LCK (0.33) | KDM4EALDH1A1USP2HPGDCYP2C19 | |
| SCHEMBL158528 | 0.81 | CA12 (0.36) | PYGLKDM4EALDH1A1USP2HPGD | |
| SCHEMBL160494 | 0.80 | — | — | |
| SCHEMBL12302082 | 0.78 | ALDH1A1 (0.30) | ALDH1A1HSD17B10TSHR | |
| SCHEMBL1439810 | 0.77 | NOTUM (0.43) | KDM4EALDH1A1HPGDHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611855-A1 | POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-8350099-B2 | Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| US-8350099-B2 | Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| US-8350099-B2 | Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2473547-A2 | POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. du Pont de Nemours and Company (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2473474-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. du Pont de Nemours and Company (US) | 2012-07-11 | — | — | EP | disclosed |
| WO-2012030352-A1 | POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20110218319-A1 | POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218319-A1 | POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218319-A1 | POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110213118-A1 | POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213118-A1 | POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213118-A1 | POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-01 | — | — | US | disclosed |
| WO-2011028791-A2 | POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028791-A2 | POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028767-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028767-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | PFAS, PAH, AFF4 | PYGL 4543/4885KDM4E 50/4885ALDH1A1 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.