Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503816 | 0.72 | ELANE (0.41) | GRM5CYP2C9 | |
| SCHEMBL1503817 | 0.72 | ELANE (0.41) | GRM5CYP2C9 | |
| SCHEMBL158914 | 0.68 | GRM5 (0.36) | GRM5CYP2C9 | |
| SCHEMBL5643720 | 0.67 | DPP4 (0.49) | GRM5 | |
| SCHEMBL5507692 | 0.64 | MTHFD2 (0.52) | — | |
| SCHEMBL29051769 | 0.63 | ACHE (0.45) | GRM5 | |
| SCHEMBL19664912 | 0.60 | TNKS2 (0.51) | — | |
| SCHEMBL3118565 | 0.60 | MTHFD2 (0.50) | — | |
| SCHEMBL322928 | 0.59 | NOTUM (0.70) | CYP2C9 | |
| SCHEMBL16219023 | 0.59 | JAK2 (0.39) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611298-A1 | BICYCLIC OXAZOLE AND THIAZOLE COMPOUNDS AND THEIR USE AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | Vanderbilt University (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012031024-A1 | BICYCLIC OXAZOLE AND THIAZOLE COMPOUNDS AND THEIR USE AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | VANDERBILT UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |