Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 7/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42313 | 0.78 | ADORA2A (0.42) | ADORA2AADORA1ERAP1PI4KAPI4K2B | |
| SCHEMBL42336 | 0.75 | PIK3CG (0.42) | ADORA2AADORA1ERAP1PI4KAPI4K2B | |
| SCHEMBL159639 | 0.75 | ADORA2A (0.40) | ADORA2AADORA1ERAP1PI4KAPI4K2B | |
| SCHEMBL843216 | 0.75 | ADORA2A (0.40) | ADORA2AADORA1ERAP1PI4KAPI4K2B | |
| SCHEMBL4581404 | 0.75 | PI4KA (0.41) | ADORA2AADORA1ERAP1PI4KAPI4K2B | |
| SCHEMBL8565 | 0.75 | ADORA2A (0.58) | ADORA2AADORA1ERAP1PI4KAPI4K2B | |
| SCHEMBL842439 | 0.75 | ADORA2A (0.40) | ADORA2AADORA1ERAP1PI4KAPI4K2B | |
| SCHEMBL12620888 | 0.75 | ADORA2A (0.40) | ADORA2AADORA1ERAP1PI4KAPI4K2B | |
| SCHEMBL953009 | 0.75 | NUDT1 (0.41) | ADORA2AADORA1ERAP1PI4KAPI4K2B | |
| SCHEMBL842890 | 0.75 | ADORA2A (0.40) | ADORA2AADORA1ERAP1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150157655-A1 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SENA RESEARCH, INC. (US) | 2015-06-11 | — | — | US | claimed |
| WO-2014003950-A2 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SENA RESEARCH, INC. (US) | 2014-01-03 | — | — | WO | claimed |
| US-7982030-B2 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2011-07-19 | — | — | US | claimed |
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-06-03 | — | — | US | claimed |
| US-20030055016-A1 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-03-20 | — | — | US | claimed |
| WO-2002077002-A2 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2002-10-03 | — | — | WO | claimed |
| US-4617189-A | Use of selenium-containing compounds for negating the toxic effects of platinum compounds used in chemotherapy, and a novel selenium-containing platinum compound and use thereof as an anti-cancer medicine | STOCKEL RICHARD F (US) | 1986-10-14 | — | — | US | claimed |
| US-10337030-B2 | Microbially-mediated method for synthesis of metal chalcogenide nanoparticles | UT-BATTELLE, LLC (US) | 2019-07-02 | — | — | US | disclosed |
| US-9909221-B2 | Controllable reductive method for synthesizing metal-containing particles | UT-BATTELLE, LLC (US) | 2018-03-06 | — | — | US | disclosed |
| US-20180010153-A1 | MICROBIALLY-MEDIATED METHOD FOR SYNTHESIS OF METAL CHALCOGENIDE NANOPARTICLES | U.S. DEPARTMENT OF ENERGY | 2018-01-11 | — | — | US | disclosed |
| US-9768333-B2 | Microbially-mediated method for synthesis of non-oxide semiconductor nanoparticles | UT-BATTELLE, LLC (US) | 2017-09-19 | — | — | US | disclosed |
| US-9637828-B2 | Electrochemical method for synthesizing metal-containing particles and other objects | UT-BATTELLE, LLC (US) | 2017-05-02 | — | — | US | disclosed |
| US-9196760-B2 | Methods for producing complex films, and films produced thereby | UT-BATTELLE, LLC (US) | 2015-11-24 | — | — | US | disclosed |
| US-20100193752-A1 | MICROBIALLY-MEDIATED METHOD FOR SYNTHESIS OF NON-OXIDE SEMICONDUCTOR NANOPARTICLES | UT-BATTELLE, LLC (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7592446-B2 | Useful in structural determinations, particularly by X-ray crystallographic techniques; useful as food supplements | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| US-20030055016-A1 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-03-20 | — | — | US | disclosed |
| WO-2002077002-A2 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2002-10-03 | — | — | WO | disclosed |
| US-4617189-A | Use of selenium-containing compounds for negating the toxic effects of platinum compounds used in chemotherapy, and a novel selenium-containing platinum compound and use thereof as an anti-cancer medicine | STOCKEL RICHARD F (US) | 1986-10-14 | — | — | US | disclosed |
| US-4536571-A | SEFL-DETOXIFYING ANTICARCINOGENIC AGENT | STOCKEL RICHARD F (US) | 1985-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055016-A1 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | SELENOI, NT5C3B, RNGTT | ADORA2A 255/4885ADORA1 551/4885ERAP1 704/4885 |
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | SELENOI, RNGTT, NT5C3B | ADORA2A 216/4885ADORA1 430/4885ERAP1 836/4885 |
| US-20150157655-A1 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SLC28A1, SLC28A2, SLC5A6 | ADORA2A 628/4885ADORA1 1489/4885ERAP1 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.