Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Glycolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL126330 | 1.00 | — | — | |
| Glycolic Acid SCHEMBL16029757 | 0.96 | CA4 (0.47) | CA4FAHD1OR51E2CASP1FFAR3 | |
| Glycolic Acid SCHEMBL9275876 | 0.96 | — | — | |
| Glycolic Acid SCHEMBL9275875 | 0.96 | CA4 (0.47) | CA4FAHD1OR51E2CASP1FFAR3 | |
| Glycolic Acid SCHEMBL16029754 | 0.96 | CA4 (0.54) | CA4FAHD1OR51E2CASP1FFAR3 | |
| Glycolic Acid SCHEMBL29008347 | 0.96 | — | — | |
| Glycolic Acid SCHEMBL31147785 | 0.96 | — | — | |
| Glycolic Acid SCHEMBL16029758 | 0.96 | — | — | |
| Glycolic Acid SCHEMBL7907676 | 0.92 | — | — | |
| Glycolic Acid SCHEMBL9841057 | 0.92 | CA4 (0.44) | CA4FAHD1OR51E2CASP1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114681386-A | Animal-derived exosome composition and application thereof in preparation of anti-aging and anti-allergic skin preparation | 和携科技有限公司 | 2022-07-01 | — | — | CN | disclosed |
| US-9758462-B2 | Nitric acid oxidation processes | RIVERTOP RENEWABLES, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-9670124-B2 | Nitric acid oxidation process | RIVERTOP RENEWABLES, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160237016-A1 | OXIDATION PROCESS | RIVERTOP RENEWABLES INC (US) | 2016-08-18 | — | — | US | disclosed |
| US-9346736-B2 | Oxidation process | RIVERTOP RENEWABLES, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20160039735-A1 | NITRIC ACID OXIDATION PROCESSES | SILICON VALLEY BANK | 2016-02-11 | — | — | US | disclosed |
| EP-2970079-A1 | IMPROVED NITRIC ACID OXIDATION PROCESSES | Rivertop Renewables, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| US-9187398-B2 | Nitric acid oxidation processes | RIVERTOP RENEWABLES, INC. (US) | 2015-11-17 | — | — | US | disclosed |
| WO-2014159694-A1 | IMPROVED NITRIC ACID OXIDATION PROCESSES | RIVERTOP RENEWABLES, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140275623-A1 | NITRIC ACID OXIDATION PROCESSES | SILICON VALLEY BANK | 2014-09-18 | — | — | US | disclosed |
| US-20140275621-A1 | OXIDATION PROCESS | SILICON VALLEY BANK | 2014-09-18 | — | — | US | disclosed |
| US-20140275622-A1 | NITRIC ACID OXIDATION PROCESS | SILICON VALLEY BANK | 2014-09-18 | — | — | US | disclosed |