Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | C1S | P09871 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16077608 | 0.96 | TPMT (0.48) | TPMTALDH1A1TSHRHPGDHCAR1 | |
| SCHEMBL347092 | 0.82 | TPMT (0.59) | TPMTALDH1A1TSHRHPGDHCAR1 | |
| SCHEMBL4360630 | 0.77 | TPMT (0.52) | TPMTALDH1A1HPGDHCAR1PARP1 | |
| Ethane SCHEMBL29138437 | 0.73 | ALDH1A1 (0.37) | TPMTALDH1A1TSHRGLRA1 | |
| SCHEMBL15700662 | 0.73 | TPMT (0.43) | TPMTALDH1A1TSHRHPGDHCAR1 | |
| SCHEMBL38576 | 0.73 | ALDH1A1 (0.40) | TPMTALDH1A1TSHRHCAR1GLRA1 | |
| SCHEMBL3968747 | 0.71 | TSHR (0.61) | ALDH1A1TSHR | |
| Toluene SCHEMBL29061412 | 0.71 | TPMT (0.52) | TPMTALDH1A1TSHRHCAR1PARP1 | |
| Acetone SCHEMBL28498158 | 0.71 | LMNA (0.38) | TPMTALDH1A1TSHRHPGDGLRA1 | |
| Acetonitrile SCHEMBL28680119 | 0.70 | TPMT (0.33) | TPMTALDH1A1TSHRGLRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851119-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2020-12-01 | — | — | US | disclosed |
| US-20200157122-A1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2020-05-21 | — | — | US | disclosed |
| US-10464951-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2019-11-05 | — | — | US | disclosed |
| EP-2970106-B1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2018-05-16 | — | — | EP | disclosed |
| US-20180079759-A1 | Boron-Containing Diacylhydrazines | INTREXON CORPORATION (US) | 2018-03-22 | — | — | US | disclosed |
| US-9512148-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2016-12-06 | — | — | US | disclosed |
| EP-2970106-A1 | BORON-CONTAINING DIACYLHYDRAZINES | Intrexon Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20150322092-A1 | Boron-Containing Diacylhydrazines | INTREXON CORPORATION (US) | 2015-11-12 | — | — | US | disclosed |
| US-9127024-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2015-09-08 | — | — | US | disclosed |
| WO-2014144380-A1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORPORATION (US) | 2014-09-18 | — | — | WO | disclosed |
| US-20140274954-A1 | Boron-Containing Diacylhydrazines | INTREXON CORPORATION | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464951-B2 | Boron-containing diacylhydrazines | CD22, BRDT, BCR | TPMT 4408/4885ALDH1A1 2724/4885TSHR 236/4885 |
| US-20150322092-A1 | Boron-Containing Diacylhydrazines | CD22, BRDT, BCR | TPMT 4408/4885ALDH1A1 2724/4885TSHR 236/4885 |
| US-10851119-B2 | Boron-containing diacylhydrazines | CD22, BRDT, BCR | TPMT 4408/4885ALDH1A1 2724/4885TSHR 236/4885 |
| US-20200157122-A1 | BORON-CONTAINING DIACYLHYDRAZINES | CD22, BRDT, BCR | TPMT 4408/4885ALDH1A1 2724/4885TSHR 236/4885 |
| US-20140274954-A1 | Boron-Containing Diacylhydrazines | CD22, BRDT, BCR | TPMT 4408/4885ALDH1A1 2724/4885TSHR 236/4885 |
| US-20180079759-A1 | Boron-Containing Diacylhydrazines | CD22, BRDT, BCR | TPMT 4408/4885ALDH1A1 2724/4885TSHR 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.