SCHEMBL1603869

SCHEMBL1603869

CC(=O)Nc1ncnc(NC(C)=O)n1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.56
CYP1A2 P05177 2/20 0.48
POLB P06746 3/20 0.47
ADORA3 P0DMS8 3/20 0.44
ADORA1 P30542 1/20 0.44
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
LMNA P02545 1/20 0.42
PTK2 Q05397 1/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPK8 P45983 1/20 0.41
MEN1 O00255 1/20 0.41
PRNP P04156 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
NPR3 P17342 2/20 0.40
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15942897 0.87 L3MBTL1 (0.48) L3MBTL1CYP1A2POLBADORA3ADORA1
SCHEMBL4392815 0.82 POLB (0.65) L3MBTL1CYP1A2POLBADORA3ADORA1
SCHEMBL3299561 0.82 POLB (0.62) L3MBTL1CYP1A2POLBADORA3ADORA1
SCHEMBL9948710 0.81 L3MBTL1 (0.50) L3MBTL1CYP1A2POLBADORA3ADORA1
SCHEMBL3470061 0.78 CYP1A2 (0.42) L3MBTL1CYP1A2LMNAPTK2KDM4E
SCHEMBL13554533 0.76 POLB (0.52) L3MBTL1CYP1A2POLBADORA3ADORA1
SCHEMBL17451125 0.76 ADORA3 (0.49) CYP1A2ADORA3ADORA1LMNAKDM4E
SCHEMBL8175532 0.76 CYP1A2 (0.41) L3MBTL1CYP1A2POLBADORA3ADORA1
SCHEMBL2491687 0.73 LMNA (0.63) L3MBTL1CYP1A2POLBADORA3ADORA1
SCHEMBL12766932 0.73 POLB (0.54) L3MBTL1CYP1A2POLBADORA3ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1368413-B1 TWO-LAYER IMAGEABLE ELEMENT COMPRISING THERMALLY REVERSIBLE POLYMERS EASTMAN KODAK CO (US) 2008-07-23 EP claimed
US-6902860-B2 Polyurethanes KODAK POLYCHROME GRAPHICS LLC (US) 2005-06-07 US claimed
US-20190271886-A1 CURVED LIQUID CRYSTAL DISPLAY DEVICE SAMSUNG DISPLAY CO LTD (KR) 2019-09-05 US disclosed
US-10338436-B2 Method of manufacturing curved liquid crystal display device and curved liquid crystal display device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-02 US disclosed
US-20180081243-A1 METHOD OF MANUFACTURING CURVED LIQUID CRYSTAL DISPLAY DEVICE AND CURVED LIQUID CRYSTAL DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-22 US disclosed
US-20180081243-A1 METHOD OF MANUFACTURING CURVED LIQUID CRYSTAL DISPLAY DEVICE AND CURVED LIQUID CRYSTAL DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-22 US disclosed
US-7919110-B2 Medical device drug release regions containing non-covalently bound polymers BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-04-05 US disclosed
EP-1843806-A2 MEDICAL DEVICE WITH DRUG RELEASE REGIONS CONTAINING PSEUDO-BLOCK COPOLYMERS Boston Scientific Limited (BB) 2007-10-17 EP disclosed
WO-2006081210-A2 MEDICAL DEVICE WITH DRUG RELEASE REGIONS CONTAINING PSEUDO - BLOCK COPOLYMERS BOSTON SCIENTIFIC SCIMED, INC. (US) 2006-08-03 WO disclosed
US-20060165753-A1 Medical device drug release regions containing non-covalently bound polymers BOSTON SCIENTIFIC SCIMED, INC. 2006-07-27 US disclosed
US-6902860-B2 Polyurethanes KODAK POLYCHROME GRAPHICS LLC (US) 2005-06-07 US disclosed