SCHEMBL1604274

SCHEMBL1604274

CCCCCCc1ccccc1Nc1ccc2ccccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 3/20 0.44
CYP3A4 P08684 2/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
LIPG Q9Y5X9 1/20 0.43
SLC16A3 O15427 1/20 0.43
TLR8 Q9NR97 1/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
HIF1A Q16665 2/20 0.40
CETP P11597 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1664994 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL7009608 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL7006946 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL570987 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL7004555 0.99 NPC1 (0.49) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL7012332 0.94 NPC1 (0.47) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL14320957 0.86 LIPG (0.51) LMNASMN1; SMN2HSD17B10LIPGTHRA
SCHEMBL11380769 0.86 LIPG (0.51) LMNASMN1; SMN2HSD17B10LIPGTHRA
SCHEMBL11213224 0.82 LIPG (0.50) EPHX1LMNASMN1; SMN2ALDH1A1HSD17B10
SCHEMBL2493912 0.82 LIPG (0.50) EPHX1LMNASMN1; SMN2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109642175-B Marine diesel engine cylinder lubricating oil composition 雪佛龙奥伦耐技术有限责任公司 2023-07-18 CN claimed
EP-3504307-B1 MARINE DIESEL CYLINDER LUBRICANT OIL COMPOSITIONS CHEVRON ORONITE TECH BV (NL) 2022-05-11 EP claimed
US-20180057765-A1 MARINE DIESEL CYLINDER LUBRICANT OIL COMPOSITIONS CHEVRON ORONITE TECHNOLOGY B.V. (NL) 2018-03-01 US claimed
EP-4263481-B1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC (US) 2025-06-18 EP disclosed
US-12173247-B2 Reaction product of an organic amine and glycidol and its use as a friction modifier HUNTSMAN PETROCHEMICAL LLC 2024-12-24 US disclosed
EP-3688126-B1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE SHELL INT RESEARCH (NL) 2024-06-12 EP disclosed
US-20240018440-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC 2024-01-18 US disclosed
EP-4263481-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER Huntsman Petrochemical LLC (US) 2023-10-25 EP disclosed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
CN-116601138-A Reaction products of organic amines and glycidol and their use as friction modifiers 亨斯迈石油化学有限责任公司 2023-08-15 CN disclosed
CN-109642175-B Marine diesel engine cylinder lubricating oil composition 雪佛龙奥伦耐技术有限责任公司 2023-07-18 CN disclosed
EP-0719853-B1 Fluid composition for use in fluid coupling TONEN CORP (JP) 2000-09-20 EP disclosed
WO-2000011122-A1 LUBRICATING OIL COMPOSITION USEFUL IN HYDRAULIC FLUIDS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2000-03-02 WO disclosed
EP-0839175-A4 LUBRICATING OIL COMPOSITION EXXON RESEARCH ENGINEERING CO (US) 1999-06-23 EP disclosed
US-5880073-A BASE OIL OF SPECIFIED COMPOSITION CONTAINING DIARYLAMINE COMPOUND AND OXYMOLYBDENUM SULFIDE DITHIOXANTHOGENATE COMPOUND TONEN CORPORATION (JP) 1999-03-09 US disclosed
EP-0860495-A2 Lubricating oil composition TONEN CORPORATION (JP) 1998-08-26 EP disclosed
EP-0839175-A1 LUBRICATING OIL COMPOSITION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-05-06 EP disclosed
US-5747429-A SILICONE OIL TONEN CORPORATION (JP) 1998-05-05 US disclosed
WO-1996037583-A1 LUBRICATING OIL COMPOSITION EXXON RESEARCH & ENGINEERING COMPANY (US) 1996-11-28 WO disclosed
EP-0719853-A2 Fluid composition for use in fluid coupling Tonen Corporation (JP) 1996-07-03 EP disclosed