SCHEMBL1664994

SCHEMBL1664994

CCCCCCCCc1ccccc1Nc1ccc2ccccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 1/20 0.48
▸ NPC1 O15118 2/20 0.48
▸ RAB9A P51151 2/20 0.48
▸ LMNA P02545 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ ALDH1A1 P00352 3/20 0.44
▸ CYP3A4 P08684 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ HPGD P15428 1/20 0.44
▸ LIPG Q9Y5X9 1/20 0.43
▸ SLC16A3 O15427 1/20 0.43
▸ TLR8 Q9NR97 1/20 0.40
▸ CYP1A2 P05177 2/20 0.40
▸ CYP2C19 P33261 2/20 0.40
▸ HIF1A Q16665 2/20 0.40
▸ CETP P11597 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ CNR1 P21554 1/20 0.37
▸ CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7009608 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL7006946 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL1604274 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL570987 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL7004555 0.99 NPC1 (0.49) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL7012332 0.94 NPC1 (0.47) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL14320957 0.86 LIPG (0.51) LMNASMN1; SMN2HSD17B10LIPGTHRA
SCHEMBL11380769 0.86 LIPG (0.51) LMNASMN1; SMN2HSD17B10LIPGTHRA
SCHEMBL11609802 0.82 LIPG (0.50) EPHX1LMNASMN1; SMN2ALDH1A1HSD17B10
SCHEMBL11213224 0.82 LIPG (0.50) EPHX1LMNASMN1; SMN2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109642175-B Marine diesel engine cylinder lubricating oil composition 雪佛龙奥伦耐技术有限责任公司 2023-07-18 — — CN claimed
EP-3504307-B1 MARINE DIESEL CYLINDER LUBRICANT OIL COMPOSITIONS CHEVRON ORONITE TECH BV (NL) 2022-05-11 — — EP claimed
US-20180057765-A1 MARINE DIESEL CYLINDER LUBRICANT OIL COMPOSITIONS CHEVRON ORONITE TECHNOLOGY B.V. (NL) 2018-03-01 — — US claimed
US-4130494-A ESTER, AMINE PHOSPHATE SALT EXXON RESEARCH & ENGINEERING CO. (US) 1978-12-19 — — US claimed
US-12173247-B2 Reaction product of an organic amine and glycidol and its use as a friction modifier HUNTSMAN PETROCHEMICAL LLC 2024-12-24 — — US disclosed
EP-3688126-B1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE SHELL INT RESEARCH (NL) 2024-06-12 — — EP disclosed
US-20240018440-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC 2024-01-18 — — US disclosed
EP-4263481-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER Huntsman Petrochemical LLC (US) 2023-10-25 — — EP disclosed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 — — US disclosed
CN-116601138-A Reaction products of organic amines and glycidol and their use as friction modifiers 亨斯迈石油化学有限责任公司 2023-08-15 — — CN disclosed
CN-109642175-B Marine diesel engine cylinder lubricating oil composition 雪佛龙奥伦耐技术有限责任公司 2023-07-18 — — CN disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 — — US disclosed
EP-0471071-B1 HIGH TEMPERATURE FUNCTIONAL FLUIDS LUBRIZOL CORP (US) 1995-08-30 — — EP disclosed
US-5366648-A Functional fluids useful at high temperatures THE LUBRIZOL CORPORATION (US) 1994-11-22 — — US disclosed
EP-0535221-A1 LUBRICATING COMPOSITIONS. LUBRIZOL CORP (US) 1993-04-07 — — EP disclosed
EP-0535217-A1 LUBRICATING COMPOSITIONS. LUBRIZOL CORP (US) 1993-04-07 — — EP disclosed
WO-1992018589-A1 LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1992-10-29 — — WO disclosed
WO-1992018588-A1 LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1992-10-29 — — WO disclosed
EP-0471071-A1 HIGH TEMPERATURE FUNCTIONAL FLUIDS. LUBRIZOL CORP (US) 1992-02-19 — — EP disclosed
WO-1991013133-A2 HIGH TEMPERATURE FUNCTIONAL FLUIDS THE LUBRIZOL CORPORATION (US) 1991-09-05 — — WO disclosed
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