SCHEMBL7006946

SCHEMBL7006946

CCCCCCCc1ccccc1Nc1ccc2ccccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 3/20 0.44
CYP3A4 P08684 2/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
LIPG Q9Y5X9 1/20 0.43
SLC16A3 O15427 1/20 0.43
TLR8 Q9NR97 1/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
HIF1A Q16665 2/20 0.40
CETP P11597 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1664994 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL7009608 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL1604274 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL570987 1.00 EPHX1 (0.48) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL7004555 0.99 NPC1 (0.49) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL7012332 0.94 NPC1 (0.47) EPHX1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL14320957 0.86 LIPG (0.51) LMNASMN1; SMN2HSD17B10LIPGTHRA
SCHEMBL11380769 0.86 LIPG (0.51) LMNASMN1; SMN2HSD17B10LIPGTHRA
SCHEMBL11213224 0.82 LIPG (0.50) EPHX1LMNASMN1; SMN2ALDH1A1HSD17B10
SCHEMBL2493912 0.82 LIPG (0.50) EPHX1LMNASMN1; SMN2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6511947-B1 A mixture of a polyphenyl ether having 4-5 aromatic rings and/or its hydrocarbon substituted group with a polyphenyl thioether having 3-5 aromatic rings, an amine antioxidant, a phosphate, and an amine salt of acid phosphate TONEN GENERAL SEKIYU K.K. (JP) 2003-01-28 US disclosed
EP-0860495-B1 Lubricating oil composition TONEN CORP (JP) 2003-01-08 EP disclosed
US-6147035-A DETERGENCY; HEAT AND OXIDATION RESISTANCE; REDUCE NITROGEN OXIDE EMISSION TONEN CORPORATION (JP) 2000-11-14 US disclosed
EP-0719853-B1 Fluid composition for use in fluid coupling TONEN CORP (JP) 2000-09-20 EP disclosed
EP-0839175-A4 LUBRICATING OIL COMPOSITION EXXON RESEARCH ENGINEERING CO (US) 1999-06-23 EP disclosed
US-5880073-A BASE OIL OF SPECIFIED COMPOSITION CONTAINING DIARYLAMINE COMPOUND AND OXYMOLYBDENUM SULFIDE DITHIOXANTHOGENATE COMPOUND TONEN CORPORATION (JP) 1999-03-09 US disclosed
EP-0860495-A2 Lubricating oil composition TONEN CORPORATION (JP) 1998-08-26 EP disclosed
EP-0839175-A1 LUBRICATING OIL COMPOSITION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-05-06 EP disclosed
US-5747429-A SILICONE OIL TONEN CORPORATION (JP) 1998-05-05 US disclosed
WO-1996037583-A1 LUBRICATING OIL COMPOSITION EXXON RESEARCH & ENGINEERING COMPANY (US) 1996-11-28 WO disclosed
EP-0719853-A2 Fluid composition for use in fluid coupling Tonen Corporation (JP) 1996-07-03 EP disclosed