Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004555 | 0.95 | NPC1 (0.49) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1664994 | 0.94 | EPHX1 (0.48) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7009608 | 0.94 | EPHX1 (0.48) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL570987 | 0.94 | EPHX1 (0.48) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7006946 | 0.94 | EPHX1 (0.48) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1604274 | 0.94 | EPHX1 (0.48) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14321012 | 0.85 | CYP3A4 (0.42) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31310666 | 0.84 | ALDH1A1 (0.52) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL26049123 | 0.84 | ALDH1A1 (0.52) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3145602 | 0.81 | CYP3A4 (0.40) | NPC1RAB9ASMN1; SMN2CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140342956-A1 | LUBRICATING OIL COMPOSITION | SHELL OIL COMPANY | 2014-11-20 | — | — | US | disclosed |
| EP-2748293-A1 | LUBRICATING OIL COMPOSITION | Shell Internationale Research Maatschappij B.V. (NL) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013037932-A1 | LUBRICATING OIL COMPOSITION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2013-03-21 | — | — | WO | disclosed |
| US-6511947-B1 | A mixture of a polyphenyl ether having 4-5 aromatic rings and/or its hydrocarbon substituted group with a polyphenyl thioether having 3-5 aromatic rings, an amine antioxidant, a phosphate, and an amine salt of acid phosphate | TONEN GENERAL SEKIYU K.K. (JP) | 2003-01-28 | — | — | US | disclosed |
| EP-0860495-B1 | Lubricating oil composition | TONEN CORP (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6147035-A | DETERGENCY; HEAT AND OXIDATION RESISTANCE; REDUCE NITROGEN OXIDE EMISSION | TONEN CORPORATION (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0719853-B1 | Fluid composition for use in fluid coupling | TONEN CORP (JP) | 2000-09-20 | — | — | EP | disclosed |
| EP-0839175-A4 | LUBRICATING OIL COMPOSITION | EXXON RESEARCH ENGINEERING CO (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5880073-A | BASE OIL OF SPECIFIED COMPOSITION CONTAINING DIARYLAMINE COMPOUND AND OXYMOLYBDENUM SULFIDE DITHIOXANTHOGENATE COMPOUND | TONEN CORPORATION (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0860495-A2 | Lubricating oil composition | TONEN CORPORATION (JP) | 1998-08-26 | — | — | EP | disclosed |
| EP-0839175-A1 | LUBRICATING OIL COMPOSITION | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5747429-A | SILICONE OIL | TONEN CORPORATION (JP) | 1998-05-05 | — | — | US | disclosed |
| WO-1996037583-A1 | LUBRICATING OIL COMPOSITION | EXXON RESEARCH & ENGINEERING COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |
| EP-0719853-A2 | Fluid composition for use in fluid coupling | Tonen Corporation (JP) | 1996-07-03 | — | — | EP | disclosed |