SCHEMBL16050239

SCHEMBL16050239

CN(O)CC(=O)Oc1ccccc1-c1ccccc1.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.50
ALDH1A1 P00352 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HTR7 P34969 1/20 0.45
TDP1 Q9NUW8 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
CHRNB2 P17787 2/20 0.44
CHRNB4 P30926 2/20 0.44
CHRNA3 P32297 2/20 0.44
CHRNA4 P43681 2/20 0.44
FABP3 P05413 2/20 0.43
FABP7 O15540 1/20 0.43
FABP5 Q01469 1/20 0.43
LMNA P02545 4/20 0.43
MAPT P10636 2/20 0.43
MAPK1 P28482 3/20 0.43
HTT P42858 2/20 0.43
USP2 O75604 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7181838 0.80 LMNA (0.49) KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL2058257 0.79 KDM4E (0.53) KDM4EALDH1A1SMN1; SMN2HTR7TDP1
SCHEMBL34470443 0.76 KDM4E (0.53) KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1
Methylamine SCHEMBL27841050 0.76 L3MBTL1 (0.47) KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL2390126 0.76 KDM4E (0.53) KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL7180832 0.76 L3MBTL1 (0.51) KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL11223694 0.76 L3MBTL1 (0.50) KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL13766122 0.76 TDP1 (0.50) KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL4389216 0.76 TDP1 (0.50) KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL8165268 0.76 MAPK1 (0.50) KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104755101-B Bio-photon is combined with chromophore 克洛克斯科技公司 2018-10-02 CN disclosed
EP-3151860-A1 THERMOSETTING BIOPHOTONIC COMPOSITIONS AND USES THEREOF Klox Technologies Inc. (CA) 2017-04-12 EP disclosed
EP-3151861-A2 SILICONE-BASED BIOPHOTONIC COMPOSITIONS AND USES THEREOF Klox Technologies Inc. (CA) 2017-04-12 EP disclosed
EP-2968561-A1 BIOPHOTONIC MATERIALS AND USES THEREOF Klox Technologies Inc. (CA) 2016-01-20 EP disclosed
WO-2015189712-A2 SILICONE-BASED BIOPHOTONIC COMPOSITIONS AND USES THEREOF KLOX TECHNOLOGIES INC. (CA) 2015-12-17 WO disclosed
WO-2015188271-A1 THERMOSETTING BIOPHOTONIC COMPOSITIONS AND USES THEREOF KLOX TECHNOLOGIES INC. (CA) 2015-12-17 WO disclosed
WO-2014138930-A1 BIOPHOTONIC MATERIALS AND USES THEREOF KLOX TECHNOLOGIES INC. (CA) 2014-09-18 WO disclosed