Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 2/20 | 0.47 |
| ▸ | FABP7 | O15540 | 1/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28731467 | 0.85 | ALOX15 (0.46) | LMNAMAPK1HTTUSP2MAPT | |
| SCHEMBL16756208 | 0.84 | ALOX15 (0.59) | LMNAHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL2058257 | 0.83 | KDM4E (0.53) | LMNAMAPK1HTTUSP2MAPT | |
| Methylamine SCHEMBL27841050 | 0.80 | L3MBTL1 (0.47) | LMNAMAPK1HTTUSP2MAPT | |
| SCHEMBL34470443 | 0.80 | KDM4E (0.53) | LMNAMAPK1HTTUSP2MAPT | |
| SCHEMBL2390126 | 0.80 | KDM4E (0.53) | LMNAMAPK1HTTUSP2MAPT | |
| SCHEMBL7180832 | 0.80 | L3MBTL1 (0.51) | LMNAMAPK1HTTUSP2MAPT | |
| SCHEMBL16050239 | 0.80 | KDM4E (0.50) | LMNAMAPK1HTTUSP2MAPT | |
| SCHEMBL23518659 | 0.79 | FABP3 (0.49) | LMNAMAPK1HTTUSP2MAPT | |
| SCHEMBL11223694 | 0.79 | L3MBTL1 (0.50) | LMNAMAPK1HTTUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305324-A1 | USE OF CHIRAL DIPHOSPHINES AS OPTICALLY ACTIVE LIGANDS | PPG-Sipsy (FR) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002012253-A1 | USE OF CHIRAL DIPHOSPHINES AS OPTICALLY ACTIVE LIGANDS | PPG-SIPSY (FR) | 2002-02-14 | — | — | WO | disclosed |