SCHEMBL160505

SCHEMBL160505

[Se]=c1[nH]cnc2nc[nH]c12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
PI4KA P42356 2/20 0.46
PI4K2B Q8TCG2 2/20 0.46
PI4K2A Q9BTU6 2/20 0.46
PI4KB Q9UBF8 2/20 0.46
LRRK2 Q5S007 2/20 0.46
LMNA P02545 2/20 0.46
DRD3 P35462 1/20 0.46
XDH P47989 1/20 0.46
G6PD P11413 1/20 0.45
PDPK1 O15530 3/20 0.42
TP53 P04637 2/20 0.42
CDK2 P24941 2/20 0.42
CHEK1 O14757 1/20 0.42
AURKA O14965 1/20 0.42
CHEK2 O96017 1/20 0.42
HSP90AA1 P07900 1/20 0.42
HSP90AB1 P08238 1/20 0.42
PRKACA P17612 1/20 0.42
CCNE1 P24864 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157322 0.72 PNP (0.62) ALDH1A1PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL30096461 0.70 ALDH1A1 (1.00) ALDH1A1PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL25381 0.70 ALDH1A1 (1.00) ALDH1A1PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL7037918 0.70 ALDH1A1 (1.00) ALDH1A1PI4KAPI4K2BPI4K2API4KB
SCHEMBL29692456 0.69 LMNA (0.57) ALDH1A1PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL560392 0.68 ALDH1A1 (0.95) ALDH1A1PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL122843 0.68 ALDH1A1 (0.95) ALDH1A1PI4KAPI4K2BPI4K2API4KB
Mercaptopurine Anhydrous SCHEMBL3895 0.68 ALDH1A1 (0.54) ALDH1A1PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL7168422 0.68 ALDH1A1 (0.95) ALDH1A1PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL2639254 0.68 ALDH1A1 (0.95) ALDH1A1PI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050148067-A1 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2005-07-07 US claimed
US-6855817-B2 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2005-02-15 US claimed
EP-1305328-A2 MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES Lyles, Mark B. (US) 2003-05-02 EP claimed
US-20020103350-A1 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2002-08-01 US claimed
WO-2002008237-A2 MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES LYLES MARK B (US) 2002-01-31 WO claimed
US-10337030-B2 Microbially-mediated method for synthesis of metal chalcogenide nanoparticles UT-BATTELLE, LLC (US) 2019-07-02 US disclosed
US-9909221-B2 Controllable reductive method for synthesizing metal-containing particles UT-BATTELLE, LLC (US) 2018-03-06 US disclosed
US-20180010153-A1 MICROBIALLY-MEDIATED METHOD FOR SYNTHESIS OF METAL CHALCOGENIDE NANOPARTICLES U.S. DEPARTMENT OF ENERGY 2018-01-11 US disclosed
US-9768333-B2 Microbially-mediated method for synthesis of non-oxide semiconductor nanoparticles UT-BATTELLE, LLC (US) 2017-09-19 US disclosed
US-9637828-B2 Electrochemical method for synthesizing metal-containing particles and other objects UT-BATTELLE, LLC (US) 2017-05-02 US disclosed
US-9196760-B2 Methods for producing complex films, and films produced thereby UT-BATTELLE, LLC (US) 2015-11-24 US disclosed
WO-2014164954-A1 ELECTROCHEMICAL METHOD FOR SYNTHESIZING METAL-CONTAINING PARTICLES AND OTHER OBJECTS UT-BATTELLE, LLC (US) 2014-10-09 WO disclosed
US-20100193752-A1 MICROBIALLY-MEDIATED METHOD FOR SYNTHESIS OF NON-OXIDE SEMICONDUCTOR NANOPARTICLES UT-BATTELLE, LLC (US) 2010-08-05 US disclosed
US-7635491-B2 Method for administering selenium for treating patients suffering from systemic inflammatory response syndrome (SIRS), and composition for implementing the treatment Forceville, Xavier (FR) 2009-12-22 US disclosed
US-7247721-B2 Providing a mixture comprising nucleic acids and a charged material comprising any cationic purine; contacting the mixture and a surface to produce a bound material, wherein the bound material comprises nucleic acids covalenty bounded to the surface LYLES MARK B 2007-07-24 US disclosed
US-20050148067-A1 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2005-07-07 US disclosed
US-6855817-B2 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2005-02-15 US disclosed
EP-1305328-A2 MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES Lyles, Mark B. (US) 2003-05-02 EP disclosed
US-20020103350-A1 Materials and methods for binding nucleic acids to surfaces LYLES MARK B (US) 2002-08-01 US disclosed
WO-2002008237-A2 MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES LYLES MARK B (US) 2002-01-31 WO disclosed