Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1973852 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Water SCHEMBL28156661 | 0.98 | KDM4E (0.50) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Ammonia Solution, Strong SCHEMBL27538381 | 0.98 | KDM4E (0.50) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Bromide SCHEMBL3646711 | 0.98 | CHRNA7 (0.50) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| SCHEMBL81238 | 0.97 | KDM4E (0.54) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrogen Sulfide SCHEMBL5998579 | 0.97 | KDM4E (0.54) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Benzene SCHEMBL29130108 | 0.97 | KDM4E (0.54) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Methyl Alcohol SCHEMBL28795266 | 0.95 | KDM4E (0.48) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Ammonia Solution, Strong SCHEMBL27273721 | 0.95 | KDM4E (0.48) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Bromide SCHEMBL117943 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3121 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743526-A2 | POLISHING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM Electronic Materials U.S.A, Inc. (US) | 2026-05-20 | — | — | EP | claimed |
| US-12448568-B2 | Etching compositions | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2025-10-21 | — | — | US | claimed |
| CN-119923173-B | N-type doping method of organic semiconductor and application thereof | 宁波天璇新材料科技有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120041847-A | Method for electrochemical synthesis of hexamethylenediamine from acrylonitrile | 万华化学集团股份有限公司 | 2025-05-27 | — | — | CN | claimed |
| EP-4551989-A1 | CLEANING COMPOSITIONS | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2025-05-14 | — | — | EP | claimed |
| CN-119976882-A | Method for synthesizing hierarchical pore molecular sieve | 中国石油大学(华东) | 2025-05-13 | — | — | CN | claimed |
| CN-119923173-A | N-type doping method of organic semiconductor and application thereof | 宁波天璇新材料科技有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119898789-A | Flower-like sphere mordenite as well as preparation method and application thereof | 中国石油化工股份有限公司 | 2025-04-29 | — | — | CN | claimed |
| US-20250066968-A1 | METHOD FOR DEGUMMING AND DECOLORIZING POLYESTER FABRIC | NAN YA PLASTICS CORPORATION (TW) | 2025-02-27 | — | — | US | claimed |
| CN-119507194-A | Method for removing glue and decoloring polyester fabric | 南亚塑胶工业股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| EP-0170986-A2 | A process for the preparation of copolycarbonates of sulfonyl diphenol | MOBAY CORPORATION (US) | 1986-02-12 | — | — | EP | claimed |
| US-4535143-A | QUATERNARY SALTS AND TERTIARY AMINE CATALYSTS; NONEMULSIFICATION MOLECULAR WEIGHT CONTROL, PROCESS | MOBAY CHEMICAL CORPORATION (US) | 1985-08-13 | — | — | US | claimed |
| US-4530830-A | Mixture containing emulsifier | REVLON, INC. (US) | 1985-07-23 | — | — | US | claimed |
| US-4521585-A | USING AMINE POLYMERIZATION CATALYST | EASTMAN KODAK COMPANY (US) | 1985-06-04 | — | — | US | claimed |
| US-4503216-A | Hydroxyl-terminated polyether-esters | EASTMAN KODAK COMPANY (US) | 1985-03-05 | — | — | US | claimed |
| EP-0119431-A1 | Method of preparing erythromycin A cyclic 11,12-carbonate | Tarchominskie Zaklady Farmaceutyczne "Polfa" (PL) | 1984-09-26 | — | — | EP | claimed |
| US-4469692-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | ALKALOIDA VEGYESZETI GYAR (HU) | 1984-09-04 | — | — | US | claimed |
| US-4335256-A | Process for manufacturing d,l-β-benzoylamino-isobutyric acid | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1982-06-15 | — | — | US | claimed |
| US-4012428-A | Method for preparing 3-methyl-2-(4-halogenophenyl)-butyronitrile | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-15 | — | — | US | claimed |
| US-4003907-A | Δ1 -1-Azacycloalkene-2-carboxylic acids and their production | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-18 | — | — | US | claimed |