Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEL | P19835 | 4/20 | 0.50 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16058694 | 0.78 | KDM4E (0.38) | JAK2JAK1KDM4E | |
| SCHEMBL9234355 | 0.76 | DAO (0.45) | DAOGPR84KDM4EMCL1 | |
| SCHEMBL5779220 | 0.72 | DRD2 (0.47) | — | |
| SCHEMBL4602524 | 0.72 | CHEK1 (0.51) | DAOSLC6A4MCL1 | |
| SCHEMBL8712639 | 0.72 | DAO (0.41) | DAOHCAR2KDM4EMCL1 | |
| SCHEMBL6536604 | 0.72 | DAO (0.45) | DAOKDM4EMCL1 | |
| SCHEMBL16593849 | 0.71 | CYP1A2 (0.52) | CELBCHECYSLTR2CYSLTR1 | |
| SCHEMBL9950280 | 0.71 | CEL (0.48) | CELBCHECYSLTR2CYSLTR1SLC6A4 | |
| SCHEMBL2495417 | 0.70 | GPR84 (0.46) | DAOGPR84KDM4EMCL1 | |
| SCHEMBL24257147 | 0.70 | PARP1 (0.48) | CELBCHESLC6A4KDM4EMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144836-A2 | CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-18 | — | — | WO | disclosed |