Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 8/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609951 | 1.00 | AKR1B1 (0.49) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| Pyrophosphoric Acid SCHEMBL2178852 | 0.93 | POLB (0.46) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL29619286 | 0.85 | TYMS (0.66) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL5665622 | 0.85 | TYMS (0.66) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL16681740 | 0.85 | AKR1B1 (0.51) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL17811602 | 0.82 | AKR1B1 (0.45) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| Folic Acid SCHEMBL8897352 | 0.79 | TYMS (0.80) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL3980437 | 0.78 | AKR1B1 (0.47) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL7639622 | 0.76 | AKR1B1 (0.46) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| Pteroic Acid SCHEMBL245981 | 0.75 | KDM4E (0.69) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160040163-A1 | DNAI FOR THE MODULATION OF GENES | PRONAI THERAPEUTICS INC (US) | 2016-02-11 | — | — | US | disclosed |
| EP-2970965-A2 | DNAI FOR THE MODULATION OF GENES | Pronai Therapeutics, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144942-A2 | DNAI FOR THE MODULATION OF GENES | PRONAI THERAPEUTICS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |