Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 9/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906514 | 0.84 | TYMS (0.62) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL15531651 | 0.84 | AKR1B1 (0.48) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL2509297 | 0.83 | NOS1 (0.46) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL2905540 | 0.82 | AKR1B1 (0.50) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL15263068 | 0.81 | AKR1B1 (0.49) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL10891557 | 0.79 | AKR1B1 (0.43) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL609951 | 0.78 | AKR1B1 (0.49) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL16058737 | 0.78 | AKR1B1 (0.49) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL851772 | 0.74 | NOS1 (0.47) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL7757815 | 0.73 | NOS1 (0.43) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324736-B1 | RAPID ANTIBIOTIC SUSCEPTIBILITY TEST | NAKANE DIAGNOSTICS INC (US) | 2009-05-13 | — | — | EP | claimed |
| CN-114957257-B | Preparation method of 5-methyltetrahydrofolate calcium | 河北冀衡药业股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-114957257-A | Preparation method of calcium 5-methyltetrahydrofolate | 河北冀衡药业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-105524066-B | (6S) 5 methyl tetrahydrofolate or its salt composite and its preparation and application | 连云港金康和信药业有限公司 | 2017-06-27 | — | — | CN | disclosed |
| US-5807688-A | ANTIBODY DIRECTED ANZYME PRODRUG THERAPY | ZENECA LIMITED (GB) | 1998-09-15 | — | — | US | disclosed |
| EP-0745673-A2 | Catalytic antibody regulated prodrug therapy | ZENECA LIMITED (GB) | 1996-12-04 | — | — | EP | disclosed |