SCHEMBL29619286

SCHEMBL29619286

Nc1nc2ncc(CNC3=CCC(C(=O)N[C@@H](CCC(=O)O)C(=O)O)C=C3)nc2c(=O)[nH]1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TYMS P04818 5/20 0.66
▸ KDM4E B2RXH2 2/20 0.66
▸ MEN1 O00255 2/20 0.66
▸ ALDH1A1 P00352 2/20 0.66
▸ POLB P06746 2/20 0.66
▸ HPGD P15428 2/20 0.66
▸ KMT2A Q03164 2/20 0.66
▸ HSD17B10 Q99714 2/20 0.66
▸ TDP1 Q9NUW8 2/20 0.66
▸ GAA P10253 1/20 0.66
▸ AKR1B1 P15121 1/20 0.66
▸ TSHR P16473 1/20 0.66
▸ PTGS2 P35354 1/20 0.66
▸ ADORA3 P0DMS8 1/20 0.55
▸ DHFR P00374 9/20 0.47
▸ GART P22102 5/20 0.47
▸ ATIC P31939 4/20 0.47
▸ TLR4 O00206 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5665622 1.00 TYMS (0.66) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL8897352 0.93 TYMS (0.80) TYMSKDM4EMEN1ALDH1A1POLB
SCHEMBL16681740 0.89 AKR1B1 (0.51) TYMSKDM4EMEN1ALDH1A1POLB
SCHEMBL609951 0.85 AKR1B1 (0.49) TYMSKDM4EMEN1ALDH1A1POLB
SCHEMBL16058737 0.85 AKR1B1 (0.49) TYMSKDM4EMEN1ALDH1A1POLB
SCHEMBL17811602 0.83 AKR1B1 (0.45) TYMSKDM4EMEN1ALDH1A1POLB
SCHEMBL2906514 0.83 TYMS (0.62) TYMSKDM4EMEN1ALDH1A1POLB
SCHEMBL27812907 0.82 TYMS (0.62) TYMSKDM4EMEN1ALDH1A1POLB
SCHEMBL7639622 0.81 AKR1B1 (0.46) TYMSKDM4EMEN1ALDH1A1POLB
Dihydrofolic Acid SCHEMBL7522026 0.81 TYMS (0.66) TYMSKDM4EMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122532-A1 VIRAL VECTORS AND PACKAGING CELL LINES UMOJA BIOPHARMA, INC. 2025-04-17 — — US disclosed
US-20250122533-A1 VIRAL VECTORS AND PACKAGING CELL LINES UMOJA BIOPHARMA, INC. 2025-04-17 — — US disclosed
US-12215337-B2 Viral vectors and packaging cell lines UMOJA BIOPHARMA, INC. (US) 2025-02-04 — — US disclosed
CN-118459590-A Anti-BTN 3A antibodies and their use in the treatment of cancer or infectious disorders 感应检查疗法公司 2024-08-09 — — CN disclosed
CN-113286819-B Anti-BTN 3A antibodies and their use in the treatment of cancer or infectious disorders 感应检查疗法公司 2024-05-24 — — CN disclosed
US-20240122978-A1 RETROVIRAL VECTOR FOR UNIVERAL RECEPTOR THERAPY UMOJA BIOPHARMA, INC. 2024-04-18 — — US disclosed
US-20230407330-A1 VECTOR SYSTEM FOR DELIVERY OF MULTIPLE POLYNUCLEOTIDES AND USES THEREOF UMOJA BIOPHARMA, INC. (US) 2023-12-21 — — US disclosed
EP-4247963-A1 VECTOR SYSTEM FOR DELIVERY OF MULTIPLE POLYNUCLEOTIDES AND USES THEREOF Umoja Biopharma, Inc. (US) 2023-09-27 — — EP disclosed
EP-4045663-A2 RETROVIRAL VECTOR FOR UNIVERAL RECEPTOR THERAPY Umoja Biopharma, Inc. (US) 2022-08-24 — — EP disclosed
WO-2022109162-A1 VECTOR SYSTEM FOR DELIVERY OF MULTIPLE POLYNUCLEOTIDES AND USES THEREOF UMOJA BIOPHARMA, INC. (US) 2022-05-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240122978-A1 RETROVIRAL VECTOR FOR UNIVERAL RECEPTOR THERAPY CD4, HAVCR2, CD40 TYMS 589/4885KDM4E 3293/4885MEN1 4670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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