SCHEMBL160620

SCHEMBL160620

Cc1ccc(CC(=O)c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.68
RAB9A P51151 4/20 0.68
L3MBTL1 Q9Y468 3/20 0.68
KMT2A Q03164 6/20 0.66
MEN1 O00255 4/20 0.66
MAPT P10636 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
PLAU P00749 1/20 0.56
CES1 P23141 2/20 0.55
CES2 O00748 1/20 0.55
SRD5A2 P31213 2/20 0.55
RECQL P46063 1/20 0.54
KDM4E B2RXH2 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CTBP2 P56545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1515693 0.92 L3MBTL1 (0.68) NPC1RAB9AL3MBTL1KMT2AMEN1
SCHEMBL5218244 0.90 NPC1 (0.81) NPC1RAB9AL3MBTL1KMT2AMEN1
SCHEMBL7199268 0.89 MAPT (0.67) NPC1RAB9AL3MBTL1KMT2AMEN1
SCHEMBL11636718 0.86 RAB9A (0.61) NPC1RAB9AL3MBTL1KMT2AMEN1
SCHEMBL28629860 0.86 NPC1 (0.71) NPC1RAB9AL3MBTL1KMT2AMEN1
Methyl Alcohol SCHEMBL11602292 0.85 MAPT (0.68) NPC1RAB9AL3MBTL1KMT2AMEN1
SCHEMBL24800 0.85 MAPT (0.73) NPC1RAB9AL3MBTL1KMT2AMEN1
SCHEMBL3919749 0.84 MAPT (0.56) NPC1RAB9AL3MBTL1KMT2AMEN1
SCHEMBL10531489 0.84 RECQL (0.59) NPC1RAB9AL3MBTL1KMT2AMEN1
SCHEMBL11382971 0.83 RAB9A (0.57) NPC1RAB9AL3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111170856-B Preparation method and application of fluoroolefin 云南民族大学 2022-04-15 CN claimed
CN-108083999-B Green preparation method of alpha-hydroxyketone 西北师范大学 2020-08-11 CN claimed
JP-62215558-A None JP disclosed
CN-115023413-B Rearrangement of dimethylphenylacrylate using zeolite 帝斯曼知识产权资产管理有限公司 2024-11-15 CN disclosed
US-20240368001-A1 SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2024-11-07 US disclosed
US-11987506-B2 Salt recovery solution and processes of use thereof AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2024-05-21 US disclosed
US-20230257284-A1 SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2023-08-17 US disclosed
CN-116282078-A Salt recovery solution and method of using the same 阿克福特斯技术有限公司 2023-06-23 CN disclosed
US-11649258-B2 Complexes JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2023-05-16 US disclosed
US-20230130025-A1 PHOTORESIST COMPOSITIONS AND METHODS FOR FABRICATING SEMICONDUCTOR DEVICE USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2023-04-27 US disclosed
CN-111225875-B Salt recovery solution and method of using salt recovery solution 阿克福特斯技术有限公司 2023-04-11 CN disclosed
US-4344954-A DIURETICS AMERICAN CYANAMID COMPANY (US) 1982-08-17 US disclosed
US-4343885-A PHOTORESISTS DYNACHEM CORPORATION (US) 1982-08-10 US disclosed
EP-0051329-A1 Photopolymerizable composition, photoinitiator mixture and curing process AKZO N.V. (NL) 1982-05-12 EP disclosed
EP-0005380-B1 PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER Dynachem Corporation (US) 1982-01-06 EP disclosed
EP-0005379-B1 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1981-12-23 EP disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0004408-A2 A process for preparing 1,7-octadiene and for activating a catalyst suitable for use in the process SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-10-03 EP disclosed
US-4009022-A Selective antagonists for triazine herbicides ROHM AND HAAS COMPANY (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649258-B2 Complexes AP2M1, AP1M1, INF2 NPC1 1998/4885RAB9A 1406/4885L3MBTL1 2204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.