Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382971 | 0.93 | RAB9A (0.57) | RAB9ANPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL3282725 | 0.88 | NPC1 (0.66) | RAB9ANPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL160620 | 0.86 | NPC1 (0.68) | RAB9ANPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL22701223 | 0.85 | CYP26A1 (0.66) | RAB9ANPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL16171153 | 0.84 | MEN1 (0.52) | RAB9ANPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL5218244 | 0.84 | NPC1 (0.81) | RAB9ANPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL3289372 | 0.81 | L3MBTL1 (0.58) | RAB9ANPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL3281032 | 0.81 | KDM4E (0.58) | RAB9ANPC1KMT2AMEN1FFAR1 | |
| SCHEMBL4183610 | 0.81 | MAPT (0.51) | RAB9ANPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL13381381 | 0.81 | CYP26A1 (0.64) | CYP26A1CYP26B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082806-A | PREPARATION OF TETRAKETONES | WRIGHT STATE UNIVERSITY (US) | 1978-04-04 | — | — | US | claimed |
| US-4082806-A | PREPARATION OF TETRAKETONES | WRIGHT STATE UNIVERSITY (US) | 1978-04-04 | — | — | US | disclosed |