Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940795 | 0.82 | THRB (0.54) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL3434424 | 0.82 | ALDH1A1 (0.46) | CES2CES1PTAFRMAPTALDH1A1 | |
| SCHEMBL3940784 | 0.82 | THRB (0.54) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL1490910 | 0.80 | CES2 (0.52) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL3431718 | 0.80 | ALDH5A1 (0.50) | CA1CA2PARP10CES2MAPT | |
| SCHEMBL3691262 | 0.79 | SLC22A6 (0.53) | KDM4E | |
| SCHEMBL10398297 | 0.78 | CES2 (0.57) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL10399404 | 0.78 | CES2 (0.57) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL10398296 | 0.78 | CES2 (0.57) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL10397662 | 0.76 | HDAC3 (0.47) | CA1CA2PARP10PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038621-A2 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | Human Biomolecular Research Institute (US) | 2016-07-06 | — | — | EP | disclosed |
| WO-2014146039-A2 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2014-09-18 | — | — | WO | disclosed |