SCHEMBL16067

SCHEMBL16067

O=S(=O)(Cl)c1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.47
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 2/20 0.46
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TRPV4 Q9HBA0 1/20 0.45
LMNA P02545 1/20 0.45
NFE2L2 Q16236 7/20 0.44
AKR1B1 P15121 1/20 0.43
PGR P06401 1/20 0.42
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250199 0.83 ALDH1A1 (0.55) HSD11B1ALDH1A1HSD17B10TDP1TSHR
SCHEMBL30697126 0.81 HSD11B1 (0.59) HSD11B1ALDH1A1HSD17B10TSHRGAA
SCHEMBL2123876 0.81 HSD11B1 (0.59) HSD11B1ALDH1A1HSD17B10TSHRGAA
SCHEMBL248010 0.81 HSD11B1 (0.59) HSD11B1ALDH1A1HSD17B10TSHRGAA
SCHEMBL6896790 0.81 HSD11B1 (0.39) HSD11B1ALDH1A1HSD17B10TSHRGAA
SCHEMBL8664415 0.81 HSD11B1 (0.46) HSD11B1ALDH1A1HSD17B10TSHRGAA
SCHEMBL13131420 0.80 HSD11B1 (0.44) HSD11B1ALDH1A1HSD17B10TSHRGAA
SCHEMBL29519135 0.80 TSHR (0.53) ALDH1A1TDP1TSHRLMNAAKR1B1
SCHEMBL18457 0.80 TSHR (0.53) ALDH1A1TDP1TSHRLMNAAKR1B1
SCHEMBL329989 0.79 HSD11B1 (0.47) HSD11B1ALDH1A1HSD17B10TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2461 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
EP-3247703-B1 IMPROVED PROCESS FOR PREPARING STATIN PRECURSOR CENTRIENT PHARMACEUTICALS NETHERLANDS B V (NL) 2024-10-16 EP claimed
CN-118084792-A Pyrazole-5-sulfonamide derivative, and preparation method and application thereof 安徽农业大学 2024-05-28 CN claimed
EP-4061132-A1 PROCESS FOR THE PREPARATION OF CHLORANTRANILIPROLE Gharda Chemicals Limited (IN) 2022-09-28 EP claimed
CN-113797900-A Adsorbing material for blood purification, preparation method and application thereof, adsorption column and blood adsorbing device 广州康盛生物科技股份有限公司 2021-12-17 CN claimed
WO-2021099978-A1 PROCESS FOR THE PREPARATION OF CHLORANTRANILIPROLE GHARDA CHEMICALS LIMITED (IN) 2021-05-27 WO claimed
CN-111472019-A Synthesis method of N-sulfonyl azole compound 安阳师范学院 2020-07-31 CN claimed
CN-106367755-B Etchant composition, method of manufacturing array substrate for liquid crystal display device using the same, and array substrate 东友精细化工有限公司 2019-12-17 CN claimed
CN-110105255-A A kind of synthetic method of mild diaryl sulfide 江西理工大学 2019-08-09 CN claimed
CN-109942600-A A kind of preparation method of Yi Dushaban 内蒙古京东药业有限公司 2019-06-28 CN claimed
CN-101100461-A Thiadiazole derivative for vulcanizing and crosslinking halogen-containing polymer and synthetic method thereof PENGCHENG REN (CN) 2008-01-09 CN claimed
CN-1886134-A Salts and polymorphs of a potent antidiabetic compound AMGEN INC (US) 2006-12-27 CN claimed
EP-1401443-A4 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORP (US) 2005-10-26 EP claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
CN-1535151-A Novel anti-infectives ʷ��˿�������ȳ�ķ���޹�˾ 2004-10-06 CN claimed
US-20040147739-A1 Novel anti-infectives SMITHKLINE BEECHAM CORPORATION 2004-07-29 US claimed
EP-1401443-A1 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION (US) 2004-03-31 EP claimed
WO-2002098424-A1 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION (US) 2002-12-12 WO claimed
US-4880576-A HALOGENATION OF ACIDS, FORMAMIDE CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 1989-11-14 US claimed
US-4666637-A Process for producing chlorobenzene sulfochloride NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1987-05-19 US claimed