Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514292 | 0.81 | TSHR (0.45) | HSD11B1TSHRALDH1A1 | |
| SCHEMBL16067 | 0.81 | HSD11B1 (0.47) | HSD11B1TRPV4GAATSHRHSD17B10 | |
| SCHEMBL15109080 | 0.81 | TSHR (0.45) | HSD11B1TSHRALDH1A1 | |
| SCHEMBL10414964 | 0.74 | ALDH1A1 (0.39) | HSD11B1TRPV4GAAHSD17B10ALDH1A1 | |
| SCHEMBL8448097 | 0.71 | CA2 (0.47) | — | |
| 1,2-Dichlorobenzene SCHEMBL2922912 | 0.70 | TSHR (0.62) | HSD11B1TSHRALDH1A1 | |
| SCHEMBL6896790 | 0.69 | HSD11B1 (0.39) | HSD11B1GAATSHRHSD17B10ALDH1A1 | |
| SCHEMBL15340796 | 0.67 | TSHR (0.39) | TSHRALDH1A1MCOLN3 | |
| SCHEMBL250199 | 0.67 | ALDH1A1 (0.55) | HSD11B1TRPV4GAATSHRHSD17B10 | |
| SCHEMBL6908682 | 0.66 | HSD11B1 (0.50) | HSD11B1GAATSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811571-A | HALOGENATING AN AROMATIC OR HETEROAROMATIC METHYL SULFIDE OR METHYL SULFOXIDE IN PRESENCE OF WATER | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |