Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248010 | 0.81 | HSD11B1 (0.59) | HSD11B1TSHRGAAHSD17B10ALDH1A1 | |
| SCHEMBL30697126 | 0.81 | HSD11B1 (0.59) | HSD11B1TSHRGAAHSD17B10ALDH1A1 | |
| SCHEMBL2123876 | 0.81 | HSD11B1 (0.59) | HSD11B1TSHRGAAHSD17B10ALDH1A1 | |
| SCHEMBL2049683 | 0.80 | TSHR (0.53) | HSD11B1TSHRALDH1A1LMNAAKR1B1 | |
| SCHEMBL16067 | 0.79 | HSD11B1 (0.47) | HSD11B1TSHRGAAHSD17B10ALDH1A1 | |
| SCHEMBL514706 | 0.77 | HSD11B1 (0.46) | HSD11B1TSHRGAAHSD17B10ALDH1A1 | |
| SCHEMBL7176672 | 0.77 | HSD11B1 (0.46) | HSD11B1TSHRGAAHSD17B10ALDH1A1 | |
| SCHEMBL6908682 | 0.77 | HSD11B1 (0.50) | HSD11B1TSHRGAAHSD17B10ALDH1A1 | |
| SCHEMBL4890031 | 0.77 | ELANE (0.54) | HSD11B1TSHRGAAHSD17B10ALDH1A1 | |
| SCHEMBL11683621 | 0.77 | HSD11B1 (0.46) | HSD11B1TSHRGAAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605310-B | Synthesis method of aza five-membered ring and three-membered ring carboxylic ester derivative and salt thereof | 都创(上海)医药科技股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| US-20220227773-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2022-07-21 | — | — | US | claimed |
| CN-112010859-B | Fused ring compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-07-19 | — | — | CN | claimed |
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AG (DE) | 2020-12-17 | — | — | US | claimed |
| WO-2020239073-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2020-12-03 | — | — | WO | claimed |
| CN-112010859-A | Fused ring compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2020-12-01 | — | — | CN | claimed |
| EP-3728214-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2020-10-28 | — | — | EP | claimed |
| CN-111727185-A | Substituted N-heterocyclyl-and N-heteroaryltetrahydropyrimidines and their salts and their use as herbicidal active substances | 拜耳公司 | 2020-09-29 | — | — | CN | claimed |
| US-20200095241-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYLPYRROLONES AND 1,2,4-THIADIAZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | US | claimed |
| US-20200079765-A1 | SUBSTITUTED HETEROARYL PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-03-12 | — | — | US | claimed |
| CN-101469011-A | Method for synthesizing polysubstituted purine nucleoside compounds | HANGZHOU RONGLI MEDICINE TECHN (CN) | 2009-07-01 | — | — | CN | claimed |
| WO-2008075184-A2 | 2-ARYL-2-FLUOROPROPANOIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE' PHA.R.MA S.P.A. (IT) | 2008-06-26 | — | — | WO | claimed |
| CN-100376242-C | 2-aryl-propionic acid and medicine composition containing same | DOMPAY CO LTD (IT) | 2008-03-26 | — | — | CN | claimed |
| CN-1612729-A | 2-Aryl-propionic acids and pharmaceutical compositions containing them | DOMPAY CO LTD (IT) | 2005-05-04 | — | — | CN | claimed |
| US-20050038119-A1 | 2-Aryl-propionic acids and pharmaceutical compositions containing them | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2005-02-17 | — | — | US | claimed |
| EP-1455773-A1 | 2-ARYL-PROPIONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.P.A. (IT) | 2004-09-15 | — | — | EP | claimed |
| WO-2003043625-A1 | 2-ARYL-PROPIONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE S.P.A. (IT) | 2003-05-30 | — | — | WO | claimed |
| US-4587336-A | PARKINSON'S DISEASE | ELI LILLY AND COMPANY (US) | 1986-05-06 | — | — | US | claimed |
| US-4068085-A | YELLOW AND RED ON POLYESTERS AND ACRYLICS | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | claimed |
| US-3943120-A | WATER INSOLUBLE | CIBA-GEIGY AG (CH) | 1976-03-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | DDT, NOTUM, AGPS | HSD11B1 600/4885TSHR 2014/4885GAA 985/4885 |
| US-20200079765-A1 | SUBSTITUTED HETEROARYL PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | DDT, HPD, PAH | HSD11B1 211/4885TSHR 1802/4885GAA 465/4885 |
| US-20200095241-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYLPYRROLONES AND 1,2,4-THIADIAZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDES | DDT, HPD, PAH | HSD11B1 530/4885TSHR 787/4885GAA 2262/4885 |
| US-20220227773-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SLC18A2, SLC6A3, SLC18A3 | HSD11B1 218/4885TSHR 1251/4885GAA 2690/4885 |
| US-20050038119-A1 | 2-Aryl-propionic acids and pharmaceutical compositions containing them | CXCR2, FPR1, CCR2 | HSD11B1 2901/4885TSHR 1315/4885GAA 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.