SCHEMBL16070697

SCHEMBL16070697

CC(C)[Si](C#Cc1ccc(CCO)cc1)(C(C)C)C(C)C

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACACB O00763 6/20 0.49
CA2 P00918 1/20 0.39
CYP4F2 P78329 2/20 0.39
CYP4A11 Q02928 2/20 0.39
TDP1 Q9NUW8 1/20 0.36
FFAR1 O14842 6/20 0.36
ALK Q9UM73 1/20 0.35
FFAR4 Q5NUL3 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025725 0.86 ALK (0.36) ACACBFFAR1ALK
SCHEMBL3345157 0.80 ACACB (0.45) ACACBCA2CYP4F2CYP4A11TDP1
SCHEMBL16070681 0.79 ACACB (0.37) ACACBALK
SCHEMBL20446355 0.79 LOXL2 (0.44) ALK
SCHEMBL28575684 0.79 ALK (0.36) ACACBALK
SCHEMBL30283119 0.77 FFAR1 (0.57) CA2FFAR1ALKFFAR4
SCHEMBL16070579 0.76 FFAR1 (0.35) ACACBFFAR1ALK
SCHEMBL27669074 0.76 CALM1 (0.41) ACACBFFAR1
SCHEMBL30283030 0.76 APP (0.44) CA2
SCHEMBL16070653 0.76 CACNA2D1 (0.36) ACACBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2975022-B1 NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF FUJIFILM TOYAMA CHEMICAL CO LTD (JP) 2019-05-08 EP disclosed
EP-3438090-A1 NOVEL METHOD FOR PRODUCING HYDROXAMIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF Toyama Chemical Co., Ltd. (JP) 2019-02-06 EP disclosed
WO-2017170884-A1 NOVEL METHOD FOR PRODUCING HYDROXAMIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF 富山化学工業株式会社 2017-10-05 WO disclosed
WO-2014142298-A1 NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF 富山化学工業株式会社 (JP) 2014-09-18 WO disclosed