SCHEMBL16070708

SCHEMBL16070708

CCCCCCCC(=O)NCCC(=O)NC(Cc1cnc[nH]1)C(=O)O

nearest known ligand 0.77

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SLC6A5 Q9Y345 1/20 0.77
▸ EPHX2 P34913 1/20 0.60
▸ FAAH O00519 4/20 0.58
▸ CNR1 P21554 2/20 0.58
▸ CNR2 P34972 2/20 0.58
▸ ITGB2 P05107 2/20 0.49
▸ ICAM1 P05362 2/20 0.49
▸ ITGAL P20701 2/20 0.49
▸ SLC15A2 Q16348 1/20 0.48
▸ NOD1 Q9Y239 2/20 0.47
▸ ALDH1A1 P00352 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ CA1 P00915 1/20 0.44
▸ CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29713992 1.00 SLC6A5 (0.77) SLC6A5EPHX2FAAHCNR1CNR2
SCHEMBL26624581 0.94 SLC6A5 (0.89) SLC6A5EPHX2FAAHCNR1CNR2
SCHEMBL17817155 0.93 SLC6A5 (0.87) SLC6A5EPHX2FAAHCNR1CNR2
SCHEMBL22034112 0.93 SLC6A5 (0.87) SLC6A5EPHX2FAAHCNR1CNR2
SCHEMBL15649758 0.93 SLC6A5 (0.87) SLC6A5EPHX2FAAHCNR1CNR2
SCHEMBL15650015 0.93 SLC6A5 (0.87) SLC6A5EPHX2FAAHCNR1CNR2
SCHEMBL17204083 0.93 SLC6A5 (0.87) SLC6A5EPHX2FAAHCNR1CNR2
SCHEMBL4348859 0.93 SLC6A5 (0.87) SLC6A5EPHX2FAAHCNR1CNR2
SCHEMBL13279669 0.93 SLC6A5 (0.87) SLC6A5EPHX2FAAHCNR1CNR2
SCHEMBL9664374 0.93 SLC6A5 (0.87) SLC6A5EPHX2FAAHCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11331305-B2 Peptides for skin rejuvenation and methods of using the same ANTEIS SA (CH) 2022-05-17 — — US disclosed
US-10543195-B2 Peptides for skin rejuvenation and methods of using the same ANTEIS SA (CH) 2020-01-28 — — US disclosed
EP-2970382-B1 PEPTIDES FOR SKIN REJUVENATION AND METHODS OF USING THE SAME ANTEIS SA (CH) 2019-09-25 — — EP disclosed
US-20160271109-A1 Peptides For Skin Rejuvenation And Methods Of Using The Same ANTEIS SA (CH) 2016-09-22 — — US disclosed
US-9375398-B2 Peptides for skin rejuvenation and methods of using the same NEOCUTIS S.A. (CH) 2016-06-28 — — US disclosed
US-20140309173-A1 Peptides For Skin Rejuvenation And Methods Of Using The Same ANTEIS SA (CH) 2014-10-16 — — US disclosed
WO-2014140890-A2 PEPTIDES FOR SKIN REJUVENATION AND METHODS OF USING THE SAME NEOCUTIS SA (CH) 2014-09-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11331305-B2 Peptides for skin rejuvenation and methods of using the same CUTA, PLOD3, MMP13 SLC6A5 2755/4885EPHX2 2518/4885FAAH 1985/4885
US-10543195-B2 Peptides for skin rejuvenation and methods of using the same CUTA, PLOD3, MMP13 SLC6A5 2755/4885EPHX2 2518/4885FAAH 1985/4885
US-20160271109-A1 Peptides For Skin Rejuvenation And Methods Of Using The Same CUTA, PLOD3, MMP13 SLC6A5 2755/4885EPHX2 2518/4885FAAH 1985/4885
US-20140309173-A1 Peptides For Skin Rejuvenation And Methods Of Using The Same CUTA, PLOD3, MMP13 SLC6A5 2755/4885EPHX2 2518/4885FAAH 1985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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