SCHEMBL1607111

SCHEMBL1607111

O=c1c(-c2ccccc2)c(O)oc2cccc(O)c12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.62
KMT2A Q03164 6/20 0.62
CYP3A4 P08684 6/20 0.62
MAPT P10636 5/20 0.62
ALOX15 P16050 3/20 0.62
MAPK1 P28482 3/20 0.62
HPGD P15428 2/20 0.62
KDM4E B2RXH2 2/20 0.62
LMNA P02545 2/20 0.62
TP53 P04637 2/20 0.62
USP2 O75604 1/20 0.62
HSD17B10 Q99714 1/20 0.62
MAOA P21397 4/20 0.56
CYP1B1 Q16678 3/20 0.54
AR P10275 3/20 0.54
CYP1A1 P04798 2/20 0.54
CYP1A2 P05177 2/20 0.54
FTO Q9C0B1 2/20 0.54
PKM P14618 2/20 0.54
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31344371 1.00 MEN1 (0.62) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL15955977 0.89 AR (0.55) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL27586284 0.86 MAOA (0.47) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL31398712 0.84 MAPT (0.44) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL11356163 0.83 MEN1 (0.55) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL571525 0.82 NTRK1 (0.52) MEN1KMT2ACYP3A4MAPTMAPK1
SCHEMBL27586405 0.82 AR (0.62) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL1255490 0.82 MEN1 (0.48) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL28278290 0.80 ALDH1A1 (0.60) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL30495370 0.80 HDAC4 (0.54) MEN1KMT2ACYP3A4MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 474 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114642241-B Composite plant polyphenol chelate and application method thereof 武汉轻工大学 2024-01-26 CN claimed
CN-114642241-A Composite plant polyphenol chelate and using method thereof 武汉轻工大学 2022-06-21 CN claimed
CN-111606881-B Synthesis method of 3',4',5',6,7, 8-hexahydroxy isoflavone and application thereof in antioxidation 中国人民解放军联勤保障部队第九〇四医院 2022-03-11 CN claimed
CN-113512018-A Flavonoid compound and preparation method and application thereof 合肥工业大学 2021-10-19 CN claimed
CN-214020732-U Preparation facilities of 4, 7 dihydroxy isoflavone 四川新一美生物科技有限公司 2021-08-24 CN claimed
CN-112205530-A Antibiotic-free feed for improving production performance of weaned piglets and preparation method thereof 广东省农业科学院动物科学研究所 2021-01-12 CN claimed
CN-111620918-A 8-beta-D-glucopyranose-4', 7-dihydroxyisoflavone FAM derivative and synthetic method thereof 辽宁中医药大学 2020-09-04 CN claimed
CN-111606881-A Synthesis method of 3 ', 4 ', 5 ', 6, 7, 8-hexahydroxy isoflavone and application thereof in antioxidation 中国人民解放军联勤保障部队第九〇四医院 2020-09-01 CN claimed
CN-111317732-A Pharmaceutical composition for preventing nephropathy of CT contrast agent and preparation method thereof 牡丹江医学院 2020-06-23 CN claimed
CN-110250394-A A kind of feed composite antioxidant and preparation method thereof 广东省农业科学院动物科学研究所 2019-09-20 CN claimed
CN-1582920-A Oral disintegrants of daidzein for treating cardio-vagal blood vessels diseases and their preparation XU XUDONG (CN) 2005-02-23 CN claimed
US-20040259181-A1 detecting beta-D-ribofuranosidase activity using novel chromogenic beta-D-ribofuranoside substrates such as catechol-beta-D-ribofuranoside or 3',4'-dihydroxyflavone-4'-beta-D-dibofuranoside; kits BURTON MICHAEL (GB) 2004-12-23 US claimed
US-20040209825-A1 Inhibition by 3-deoxyflavonoids of T-lymphocyte activation and therapies related thereto LAHEY THOMAS P (US) 2004-10-21 US claimed
CN-1528286-A Soybean aglycone drop pill and preparing method thereof 南昌弘益科技有限公司 2004-09-15 CN claimed
US-6774142-B2 MAY BE ADMINISTERED ALONG WITH RUTIN, A RUTIN CONGENER AND/OR A RUTIN DERIVATIVE. IMMUNOBIOTICS, INC. 2004-08-10 US claimed
EP-1438424-A2 ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY Burton, Michael (GB) 2004-07-21 EP claimed
WO-2003035897-A2 ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2003-05-01 WO claimed
CN-1306434-A Composition for preventing and/or treating osteoporosis and pathologies resulting from menopausal syndrome SIGMA TAU HEALTHSCIENCE SPA (IT) 2001-08-01 CN claimed
CN-1259130-A Preparation of isoflavones from leguminous plants NOVOGEN INC (US) 2000-07-05 CN claimed
WO-1998021946-A1 COMPOSITION AND TREATMENT FOR PERSISTENT REPRODUCTIVE TRANSITION SYMPTOMS INTERNUTRIA, INC. (US) 1998-05-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040209825-A1 Inhibition by 3-deoxyflavonoids of T-lymphocyte activation and therapies related thereto HLA-DRB1, NFATC1, CD4 MEN1 4047/4885KMT2A 3519/4885CYP3A4 105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.