Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16072731 | 0.91 | GNAI3 (0.59) | GNAI3GNAO1GNAI1ALDH1A1KDM4E | |
| SCHEMBL19002634 | 0.91 | GNAI3 (0.52) | GNAI3GNAO1GNAI1ALDH1A1HSD11B1 | |
| SCHEMBL16072733 | 0.88 | GNAI3 (0.68) | GNAI3GNAO1GNAI1ALDH1A1NPC1 | |
| SCHEMBL16072734 | 0.88 | GNAI3 (0.68) | GNAI3GNAO1GNAI1ALDH1A1NPC1 | |
| SCHEMBL13498641 | 0.87 | GNAI3 (0.51) | GNAI3GNAO1GNAI1ALDH1A1HSD11B1 | |
| SCHEMBL19049434 | 0.87 | AKR1C3 (0.46) | GNAI3GNAO1GNAI1ALDH1A1AKR1C3 | |
| SCHEMBL13498561 | 0.86 | GNAI3 (0.50) | GNAI3GNAO1GNAI1ALDH1A1HSD11B1 | |
| SCHEMBL10274497 | 0.84 | GNAI3 (0.58) | GNAI3GNAO1GNAI1ALDH1A1HSD11B1 | |
| SCHEMBL13498645 | 0.84 | GNAI3 (0.56) | GNAI3GNAO1GNAI1ALDH1A1DRD2 | |
| SCHEMBL23716522 | 0.83 | CHRNB2 (0.50) | GNAI3GNAO1GNAI1ALDH1A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC | 2017-06-22 | — | — | US | disclosed |
| US-20160355859-A1 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2016-12-08 | — | — | US | disclosed |
| US-20140274903-A1 | USE OF GALACTOSE OXIDASE FOR SELECTIVE CHEMICAL CONJUGATION OF PROTRACTOR MOLECULES TO PROTEINS OF THERAPEUTIC INTEREST | NOVO NORDISK HEALTHCARE AG (CH) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140274903-A1 | USE OF GALACTOSE OXIDASE FOR SELECTIVE CHEMICAL CONJUGATION OF PROTRACTOR MOLECULES TO PROTEINS OF THERAPEUTIC INTEREST | GALE, GALNT2, GALNT1 | GNAI3 1106/4885GNAO1 212/4885GNAI1 1120/4885 |
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | MAPK6, MAP3K6, MAPK4 | GNAI3 861/4885GNAO1 1452/4885GNAI1 680/4885 |
| US-20160355859-A1 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | TGM2, TGM3, TGM1 | GNAI3 1834/4885GNAO1 3325/4885GNAI1 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.