Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264481 | 0.77 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3279378 | 0.77 | GRIN2D (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL10388718 | 0.77 | ACHE (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3280289 | 0.73 | SELL (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1578480 | 0.73 | KMT2A (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL19596683 | 0.73 | CA1 (0.64) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28321393 | 0.73 | ACHE (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9437376 | 0.73 | TRPA1 (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3282798 | 0.71 | ALDH1A1 (0.42) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28157640 | 0.70 | CYP3A4 (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2482809-B1 | COMPOSITIONS COMPRISING AN ANTI-INFLAMMATORY BLEND | JOHNSON & JOHNSON CONSUMER INC (US) | 2018-06-13 | — | — | EP | disclosed |
| US-9629794-B2 | Compositions comprising an NFκB-inhibitor and a tropoelastin promoter | JOHNSON & JOHNSON CONSUMER INC. (US) | 2017-04-25 | — | — | US | disclosed |
| EP-2319488-B1 | Compositions comprising an NFkB-inhibitor and a tropoelastin promoter | JOHNSON & JOHNSON CONSUMER (US) | 2016-07-20 | — | — | EP | disclosed |
| EP-2316413-B1 | Compositions comprising an nfkb-inhibitor and a non-retinoid collagen promoter | JOHNSON & JOHNSON CONSUMER (US) | 2016-07-20 | — | — | EP | disclosed |
| US-9375395-B2 | Compositions comprising an NFκB-inhibitor and a tropoelastin promoter | JOHNSON & JOHNSON CONSUMER INC. (US) | 2016-06-28 | — | — | US | disclosed |
| US-9289361-B2 | Compositions comprising an NFκB-inhibitor and a non-retinoid collagen promoter | JOHNSON & JOHNSON CONSUMER INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150064292-A1 | COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER | KENVUE BRANDS LLC | 2015-03-05 | — | — | US | disclosed |
| US-8906432-B2 | Compositions comprising an NFκB-inhibitor and a non-retinoid collagen promoter | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20130171281-A1 | COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130164393-A1 | Compositions Comprising an NFkB-Inhibitor and a Non-Retinoid Collagen Promoter | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-8318217-B2 | Compositions comprising an anti-inflammatory blend | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2012-11-27 | — | — | US | disclosed |
| EP-2482809-A1 | COMPOSITIONS COMPRISING AN ANTI-INFLAMMATORY BLEND | Johnson & Johnson Consumer Companies, Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| EP-2319488-A2 | Compositions comprising an NFkB-inhibitor and a tropoelastin promoter | Johnson & Johnson Consumer Companies, Inc. (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-2316413-A2 | Compositions comprising an nfkb-inhibitor and a non-retinoid collagen promoter | Johnson and Johnson Consumer Companies, Inc. (US) | 2011-05-04 | — | — | EP | disclosed |
| US-20110081431-A1 | COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A NON-RETINOID COLLAGEN PROMOTER | KENVUE BRANDS LLC | 2011-04-07 | — | — | US | disclosed |
| US-20110081430-A1 | COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110081433-A1 | COMPOSITIONS COMPRISING AN ANTI-INFLAMMATORY BLEND | JOHNSON & JOHNSON CONSUMER INC. | 2011-04-07 | — | — | US | disclosed |
| WO-2011041648-A1 | COMPOSITIONS COMPRISING AN ANTI-INFLAMMATORY BLEND | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2011-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110081431-A1 | COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A NON-RETINOID COLLAGEN PROMOTER | NFKBIA, NFRKB, NFKB1 | GRIN2D 4839/4885GRIN3B 4316/4885GRIN1 4307/4885 |
| US-20110081430-A1 | COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER | NFKBIA, NFKB1, NFKB2 | GRIN2D 4885/4885GRIN3B 4713/4885GRIN1 4767/4885 |
| US-20150064292-A1 | COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER | NFKBIA, NFKB1, NFKB2 | GRIN2D 4885/4885GRIN3B 4713/4885GRIN1 4767/4885 |
| US-20110081433-A1 | COMPOSITIONS COMPRISING AN ANTI-INFLAMMATORY BLEND | NFKBIA, NFKB2, NFKB1 | GRIN2D 3991/4885GRIN3B 2393/4885GRIN1 2403/4885 |
| US-20130171281-A1 | COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER | NFKBIA, NFKB1, NFKB2 | GRIN2D 4885/4885GRIN3B 4713/4885GRIN1 4767/4885 |
| US-20130164393-A1 | Compositions Comprising an NFkB-Inhibitor and a Non-Retinoid Collagen Promoter | NFKBIA, NFRKB, NFKB1 | GRIN2D 4839/4885GRIN3B 4316/4885GRIN1 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.