Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2902840 | 0.95 | LMNA (0.48) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2912510 | 0.94 | LMNA (0.49) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL4120039 | 0.92 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1607377 | 0.84 | LMNA (0.51) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL15503157 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL277446 | 0.81 | LMNA (0.50) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12109353 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 | |
| Valeric Acid SCHEMBL29796187 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5880878 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL15315496 | 0.79 | FAAH (0.41) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073988-A | Anti-CDH3 humanized antibody, drug conjugate thereof, and utilization of same | PERSEUS PROTEOMICS INC | 2015-11-18 | — | — | CN | claimed |
| CN-104220595-A | Agent conjugates of anti-CDH 3 (P-cadherin) antibodies | PERSEUS PROTEOMICS INC | 2014-12-17 | — | — | CN | claimed |
| EP-2414395-A1 | ANTI-FCRH5 ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE | Genentech, Inc. (US) | 2012-02-08 | — | — | EP | claimed |
| WO-2010114940-A1 | ANTI-FCRH5 ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE | GENENTECH, INC. (US) | 2010-10-07 | — | — | WO | claimed |
| CN-118076376-A | TGF-beta bearing antigen presenting polypeptide complexes and methods of use thereof | 库尔生物制药有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-116437952-A | T cell modulating polypeptides with conjugation sites and methods of use thereof | 库尔生物制药有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-111886241-A | Multimeric T cell modulating polypeptides and methods of use thereof | 库尔生物制药有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-110511279-A | Oncostatin M receptor antigen binding proteins | KINIKSA PHARMACEUTICALS LTD | 2019-11-29 | — | — | CN | disclosed |
| CN-105555803-B | Oncostatin M receptor antigen binding proteins | 基尼克萨制药有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-107513105-B | Oncostatin M receptor antigen binding proteins | 基尼克萨制药有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-109689107-A | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-108779146-A | Peptide derivant and application thereof | 东丽株式会社 | 2018-11-09 | — | — | CN | disclosed |
| CN-102770456-B | Multispecific antibodies, antibody analogs, compositions and methods | 弗·哈夫曼-拉罗切有限公司 | 2018-04-06 | — | — | CN | disclosed |
| CN-107513105-A | Oncostatin M receptor antigen binding proteins | 基尼克萨制药有限公司 | 2017-12-26 | — | — | CN | disclosed |
| CN-107337734-A | Multi-specificity antibody, antibody analog, composition and method | 弗·哈夫曼-拉罗切有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-105073988-A | Anti-CDH3 humanized antibody, drug conjugate thereof, and utilization of same | PERSEUS PROTEOMICS INC | 2015-11-18 | — | — | CN | disclosed |
| CN-104797600-A | Antibody capable of specifically recognizing transferrin receptor | NAT UNIVERSITY CORP UNIVERSITY OF MIYAZAKI | 2015-07-22 | — | — | CN | disclosed |
| CN-104220595-A | Agent conjugates of anti-CDH 3 (P-cadherin) antibodies | PERSEUS PROTEOMICS INC | 2014-12-17 | — | — | CN | disclosed |
| CN-102770456-A | Multispecific antibodies, antibody analogs, compositions and methods | GENENTECH INC | 2012-11-07 | — | — | CN | disclosed |