SCHEMBL160744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL162542	0.86	ALDH1A1 (0.43)	MAPTALDH1A1NPC1RAB9AMEN1
	SCHEMBL108390	0.84	MAPT (0.50)	MAPTALDH1A1NPC1RAB9AMEN1
	SCHEMBL162723	0.83	TSHR (0.46)	ALDH1A1NPC1RAB9ACYP1A2CYP2C19
	SCHEMBL9454202	0.82	RAB9A (0.66)	MAPTALDH1A1NPC1RAB9AMEN1
	SCHEMBL163124	0.81	TSHR (0.45)	MAPTALDH1A1MEN1KMT2ASMN1; SMN2
	SCHEMBL1476131	0.81	MAPT (0.47)	MAPTALDH1A1NPC1RAB9AMEN1
	SCHEMBL29120041	0.81	MAPT (0.51)	MAPTALDH1A1NPC1RAB9AMEN1
	SCHEMBL28402654	0.81	ALDH1A1 (0.55)	MAPTALDH1A1NPC1RAB9AMEN1
	SCHEMBL5820798	0.81	MAPT (0.47)	MAPTALDH1A1NPC1RAB9AMEN1
	SCHEMBL2594514	0.81	ALDH1A1 (0.48)	MAPTALDH1A1NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.