Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | IGF2R | P11717 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081494 | 0.93 | TLR4 (0.43) | TLR4PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL2964015 | 0.88 | PRKCA (0.42) | TLR4PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL29564847 | 0.88 | PRKCA (0.42) | TLR4PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL2964018 | 0.88 | PRKCA (0.42) | TLR4PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL8014983 | 0.85 | TLR4 (0.41) | TLR4PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL8013796 | 0.85 | TLR4 (0.41) | TLR4PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL24621714 | 0.83 | SLC2A1 (0.38) | TLR4PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL13214827 | 0.83 | SLC2A1 (0.38) | TLR4PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL10233847 | 0.83 | SLC2A1 (0.38) | TLR4PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL19779374 | 0.83 | FBP1 (0.38) | TLR4PRKCAPRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180015167-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2018-01-18 | — | — | US | disclosed |
| US-20140271601-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | INVIVO THERAPEUTICS CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015167-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | TREH, TBCA, BMP2 | TLR4 3108/4885PRKCA 1828/4885PRKD3 1822/4885 |
| US-20140271601-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | TREH, TBCA, BMP2 | TLR4 3108/4885PRKCA 1828/4885PRKD3 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.