Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16079005 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MAPTPKMMAOANOX1 | |
| SCHEMBL16075978 | 0.76 | MAOA (0.34) | ALDH1A1MAPTMAOANOX1 | |
| SCHEMBL762766 | 0.68 | MAOA (0.68) | ALDH1A1MAPTPKMMAOANOX1 | |
| SCHEMBL12511896 | 0.68 | MAPT (0.44) | ALDH1A1MAPTPKMMAOANOX1 | |
| SCHEMBL18550499 | 0.60 | MAOA (0.40) | ALDH1A1MAPTMAOA | |
| SCHEMBL16079012 | 0.59 | ALDH1A1 (0.37) | ALDH1A1MAPTPKM | |
| SCHEMBL8845015 | 0.59 | — | — | |
| SCHEMBL19035967 | 0.58 | MAOA (0.40) | MAPTMAOANOX1 | |
| SCHEMBL16079002 | 0.57 | ALDH1A1 (0.45) | ALDH1A1MAPTPKMNOX1 | |
| SCHEMBL2816698 | 0.57 | ALDH1A1 (0.65) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275169-A1 | Combination Therapies for Enhancing Protein Degradation | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275169-A1 | Combination Therapies for Enhancing Protein Degradation | HSPA2, HSPBP1, HSPH1 | ALDH1A1 2288/4885MAPT 27/4885PKM 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.