Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16122917 | 0.94 | ALDH1A1 (0.46) | SIGMAR1ALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL16079061 | 0.85 | ALDH1A1 (0.45) | SIGMAR1ALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL19487702 | 0.85 | ALDH1A1 (0.43) | SIGMAR1ALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL16077714 | 0.83 | ALDH1A1 (0.45) | SIGMAR1ALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL16079059 | 0.83 | GNAI3 (0.46) | SIGMAR1ALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL16077715 | 0.82 | ALDH1A1 (0.43) | SIGMAR1ALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL16077705 | 0.82 | GNAI3 (0.43) | ALDH1A1GNAI3GNAO1GNAI1OPRD1 | |
| SCHEMBL24703430 | 0.81 | GNAI3 (0.45) | SIGMAR1ALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL19520072 | 0.80 | ALDH1A1 (0.44) | SIGMAR1ALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL22168402 | 0.79 | POLB (0.46) | SIGMAR1ALDH1A1CHRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140271526-A1 | ANTIMICROBIAL POLYAMIDE COMPOSITIONS AND MASTITIS TREATMENT | MERIAL LIMITED (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140271526-A1 | ANTIMICROBIAL POLYAMIDE COMPOSITIONS AND MASTITIS TREATMENT | PUF60, PARG, PAM | SIGMAR1 163/4885ALDH1A1 4386/4885CHRM1 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.