Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16077707 | 0.96 | GNAI3 (0.48) | GNAI3GNAO1GNAI1OPRD1POLB | |
| SCHEMBL16076285 | 0.95 | OPRD1 (0.42) | GNAI3GNAO1GNAI1OPRD1POLB | |
| SCHEMBL16077706 | 0.92 | POLB (0.48) | GNAI3GNAO1GNAI1OPRD1POLB | |
| SCHEMBL16076286 | 0.89 | USP2 (0.43) | GNAI3GNAO1GNAI1OPRD1POLB | |
| SCHEMBL16122917 | 0.88 | ALDH1A1 (0.46) | GNAI3GNAO1GNAI1OPRD1POLB | |
| SCHEMBL16076284 | 0.83 | POLB (0.38) | GNAI3GNAO1GNAI1POLBHTT | |
| SCHEMBL16079041 | 0.82 | SIGMAR1 (0.48) | GNAI3GNAO1GNAI1OPRD1POLB | |
| SCHEMBL5956990 | 0.80 | SMN1; SMN2 (0.54) | OPRD1HTTCASP2ALDH1A1TDP1 | |
| SCHEMBL24412614 | 0.79 | POLB (0.57) | GNAI3GNAO1GNAI1OPRD1POLB | |
| SCHEMBL19487702 | 0.79 | ALDH1A1 (0.43) | GNAI3GNAO1GNAI1OPRD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160208046-A1 | AMINE FUNCTIONAL POLYAMIDES | GENZYME CORPORATION | 2016-07-21 | — | — | US | disclosed |
| US-9326994-B2 | Amine functional polyamides | GENZYME CORPORATION (US) | 2016-05-03 | — | — | US | disclosed |
| US-20140275469-A1 | AMINE FUNCTIONAL POLYAMIDES | GENZYME CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160208046-A1 | AMINE FUNCTIONAL POLYAMIDES | PAM, ASNS, PARN | GNAI3 3042/4885GNAO1 2569/4885GNAI1 2420/4885 |
| US-20140275469-A1 | AMINE FUNCTIONAL POLYAMIDES | PAM, ASNS, PARN | GNAI3 3042/4885GNAO1 2569/4885GNAI1 2420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.