Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ACACA | Q13085 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226910 | 0.92 | L3MBTL1 (0.58) | L3MBTL1ATMCNR1HSD11B1TDP1 | |
| Hydrochloric Acid SCHEMBL14777717 | 0.91 | L3MBTL1 (0.57) | L3MBTL1ATMCNR1HSD11B1TDP1 | |
| SCHEMBL16087283 | 0.89 | L3MBTL1 (0.63) | L3MBTL1RORCATMTDP1SMN1; SMN2 | |
| SCHEMBL16087252 | 0.87 | SCN9A (0.51) | L3MBTL1RORCATMTDP1SCN9A | |
| SCHEMBL16087187 | 0.87 | PKM (0.54) | L3MBTL1ATMTDP1SMN1; SMN2GAA | |
| SCHEMBL16087385 | 0.87 | L3MBTL1 (0.66) | L3MBTL1ATMHSD11B1TDP1SMN1; SMN2 | |
| SCHEMBL16087246 | 0.87 | LMNA (0.56) | L3MBTL1RORCATMHSD11B1SMN1; SMN2 | |
| SCHEMBL16087362 | 0.84 | L3MBTL1 (0.54) | L3MBTL1ATMHSD11B1TDP1SCN9A | |
| SCHEMBL16087255 | 0.81 | KMT2A (0.53) | ATMSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL1945511 | 0.80 | L3MBTL1 (0.81) | L3MBTL1ATMCNR1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533782-B1 | PIPERAZINE DERIVATIVES FOR BLOCKING Cav2.2 CALCIUM CHANNELS | CONVERGENCE PHARMACEUTICALS (GB) | 2014-09-24 | — | — | EP | claimed |