SCHEMBL1608810

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1609251	0.75	MAOB (0.36)	KDM4EGRIN2DGRIN3BGRIN1GRIN2A
	SCHEMBL7432202	0.74	KMT2A (0.36)	KDM4EGRIN2DGRIN3BGRIN1GRIN2A
	SCHEMBL15680307	0.73	GAA (0.49)	KDM4ESMN1; SMN2GAAPRKCGPRKCA
	SCHEMBL1608266	0.73	NUAK1 (0.43)	SMN1; SMN2GRIN2DGRIN3BGRIN1GRIN2A
	SCHEMBL3815519	0.73	ALDH1A1 (0.33)	PRKCGPRKCAPRKCDMAOAALDH1A1
	SCHEMBL7432592	0.72	KMT2A (0.39)	KDM4EGAAGRIN2DGRIN3BGRIN1
	SCHEMBL7428171	0.72	KMT2A (0.39)	KDM4EPRKCGPRKCAPRKCDGRIN2D
	SCHEMBL18311415	0.71	GAA (0.50)	KDM4ESMN1; SMN2GAAPRKCGPRKCA
	SCHEMBL1609319	0.71	ALDH1A1 (0.41)	KDM4EGAAPRKCGPRKCAPRKCD
	SCHEMBL6214355	0.71	GPR35 (0.48)	KDM4ESMN1; SMN2GAAMAOAGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.