SCHEMBL1609251

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3815519	0.89	ALDH1A1 (0.33)	MAOBMAOAALDH1A1ALOX5NUAK1
	SCHEMBL1609751	0.78	RECQL (0.38)	MAOAMAPTKDM4EALDH1A1RECQL
	SCHEMBL1608810	0.75	KDM4E (0.44)	MAOAMAPTGPR35MEN1HPGD
	SCHEMBL15680228	0.73	ALOX5 (0.36)	MAOBMAOAALOX5NUAK1IGF1R
	SCHEMBL1608266	0.73	NUAK1 (0.43)	MAOAGPR35S100A4NUAK1IGF1R
	SCHEMBL1609319	0.71	ALDH1A1 (0.41)	MAPTGPR35MEN1HPGDKMT2A
	SCHEMBL2049186	0.67	PGR (0.41)	MAOBMAOAMAPTMEN1KMT2A
	SCHEMBL2041366	0.67	POLB (0.39)	MAOBMAOAMAPTHPGDKMT2A
	SCHEMBL29947934	0.67	PGR (0.41)	MAOBMAOAMAPTMEN1KMT2A
	SCHEMBL1609100	0.66	IMPDH1 (0.45)	HPGDKDM4EALDH1A1CYP1A2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.