Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | TOP2A | P11388 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16088696 | 0.95 | AKR1C3 (0.55) | AKR1C3AKR1C2MMP13RAB9ANPC1 | |
| SCHEMBL16127862 | 0.92 | MMP13 (0.62) | AKR1C3AKR1C2MMP13RAB9ANPC1 | |
| SCHEMBL23864323 | 0.90 | NPC1 (0.51) | AKR1C3AKR1C2MMP13RAB9ANPC1 | |
| SCHEMBL16127863 | 0.87 | MMP13 (0.62) | AKR1C3AKR1C2MMP13RAB9ANPC1 | |
| SCHEMBL16088644 | 0.82 | KMT2A (0.60) | APEX1NR1H4KMT2AEPHX2ALDH1A1 | |
| SCHEMBL16088690 | 0.80 | APEX1 (0.79) | APEX1NR1H4KMT2AEPHX2L3MBTL1 | |
| SCHEMBL16127889 | 0.79 | APEX1 (0.77) | RAB9ANPC1APEX1KMT2AMEN1 | |
| SCHEMBL22113961 | 0.78 | MMP13 (0.58) | AKR1C3AKR1C2MMP13RAB9ANPC1 | |
| SCHEMBL17531724 | 0.78 | MMP13 (0.71) | MMP13RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL14126222 | 0.77 | EPHX2 (0.59) | MMP13RAB9ANPC1TOP2ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9452170-B2 | Compounds and methods for inducing chondrogenesis | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-09-27 | — | — | US | disclosed |
| US-20160045514-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-02-18 | — | — | US | disclosed |
| US-20140271955-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160045514-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | COL2A1, BMP4, COL1A1 | AKR1C3 1767/4885AKR1C2 1853/4885MMP13 10/4885 |
| US-20140271955-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | COL2A1, BMP4, COL1A1 | AKR1C3 1767/4885AKR1C2 1853/4885MMP13 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.