Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29485544 | 0.80 | NR1H4 (0.52) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL6979487 | 0.78 | NR1H4 (0.57) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL8433800 | 0.77 | NR1H4 (0.45) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL8437871 | 0.76 | NR1H4 (0.44) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL2164727 | 0.73 | NOTUM (0.45) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL8293809 | 0.73 | NOTUM (0.45) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL2164730 | 0.73 | NOTUM (0.45) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL3618510 | 0.72 | HDAC6 (0.42) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL1609983 | 0.71 | NOTUM (0.50) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL77636 | 0.70 | NR1H4 (0.57) | NR1H4RAB9ANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086893-A1 | OXA- AND THIADIAZOLES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | VERNALIS (OXFORD) LTD (GB) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086893-A1 | OXA- AND THIADIAZOLES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | MMP12, TIMP3, MMP9 | NR1H4 1726/4885RAB9A 3656/4885NPC1 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.