SCHEMBL1609290

SCHEMBL1609290

CCCCC[CH]c1cc(C)cc(C)c1C

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
TRPV1 Q8NER1 2/20 0.32
FAAH O00519 2/20 0.31
CRHR1 P34998 2/20 0.31
PDE5A O76074 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.31
POLB P06746 1/20 0.30
HPGD P15428 1/20 0.30
CYP19A1 P11511 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1611562 0.98 TSHR (0.38) TSHRTRPV1FAAHPDE5A
SCHEMBL1610541 0.98 TSHR (0.38) TSHRTRPV1FAAHPDE5A
SCHEMBL1610231 0.94 PDE5A (0.35) TSHRCRHR1PDE5APOLBHPGD
SCHEMBL1610690 0.86 CRHR1 (0.30) CRHR1
SCHEMBL1611373 0.83 TSHR (0.35) TSHRTRPV1FAAHCYP19A1
SCHEMBL1611498 0.81 TSHR (0.39) TSHRTRPV1FAAHCYP19A1
SCHEMBL1613238 0.81 TSHR (0.39) TSHRTRPV1FAAHCYP19A1
SCHEMBL1610750 0.80 RAPGEF4 (0.33) KMT2A
SCHEMBL1610993 0.79 SIRT2 (0.36) TSHRFAAHSIRT2POLBHPGD
SCHEMBL1610402 0.78 ALDH1A1 (0.43) PDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110087034-A1 Organic Semiconductor Material SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-04-14 US disclosed
EP-2248818-A1 ORGANIC SEMICONDUCTOR MATERIAL Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110087034-A1 Organic Semiconductor Material OR10J3, TST, OR51E2 TSHR 2994/4885TRPV1 1124/4885FAAH 4640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.