Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | STS | P08842 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16093442 | 0.97 | FAAH (0.36) | FAAHITGB3ITGAVPPARGSTS | |
| SCHEMBL12267044 | 0.87 | TBXAS1 (0.46) | TBXAS1MAPTALDH1A1 | |
| SCHEMBL1688321 | 0.82 | FAAH (0.38) | FAAHITGB3ITGAVPPARG | |
| SCHEMBL13260587 | 0.78 | TRPV1 (0.44) | FAAHSTSHSD17B10TRPV1MEN1 | |
| SCHEMBL16093430 | 0.77 | FAAH (0.34) | FAAHPPARGMPOKDM4EALDH1A1 | |
| SCHEMBL13880533 | 0.76 | FAAH (0.39) | FAAHITGB3ITGAVPPARG | |
| SCHEMBL12809270 | 0.73 | FAAH (0.34) | FAAHPPARGSTSHSD17B10TRPV1 | |
| SCHEMBL13226753 | 0.73 | ALDH1A1 (0.32) | FAAHPPARGSTSMEN1KMT2A | |
| SCHEMBL13892164 | 0.73 | FAAH (0.38) | FAAHSTSHSD17B10ALDH1A1 | |
| SCHEMBL13113625 | 0.72 | CASP2 (0.40) | FAAHSTSALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841249-B2 | Growth hormones with prolonged in-vivo efficacy | NOVO NORDISK A/S (DK) | 2014-09-23 | — | — | US | disclosed |