Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 13/20 | 0.65 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599867 | 0.83 | ERN1 (0.47) | ERN1XDH | |
| SCHEMBL7368834 | 0.79 | ERN1 (0.56) | ERN1XDHGPR35 | |
| SCHEMBL928630 | 0.79 | ERN1 (1.00) | ERN1XDH | |
| SCHEMBL2925564 | 0.78 | ERN1 (0.59) | ERN1XDHGPR35 | |
| SCHEMBL2918547 | 0.78 | ERN1 (0.59) | ERN1XDH | |
| SCHEMBL9328126 | 0.74 | GPR35 (0.57) | ERN1XDHGPR35 | |
| SCHEMBL16838210 | 0.73 | ERN1 (0.56) | ERN1XDH | |
| SCHEMBL29441809 | 0.73 | ERN1 (0.67) | ERN1GPR35 | |
| SCHEMBL831073 | 0.73 | ERN1 (0.67) | ERN1GPR35 | |
| SCHEMBL15783651 | 0.73 | XDH (0.71) | ERN1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9622988-B2 | Small molecule xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-04-18 | — | — | US | disclosed |
| US-9622988-B2 | Small molecule xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-04-18 | — | — | US | disclosed |
| US-9610257-B2 | Small molecule xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-04-04 | — | — | US | disclosed |
| US-9610257-B2 | Small molecule xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-04-04 | — | — | US | disclosed |
| US-9585848-B2 | Small molecule xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-03-07 | — | — | US | disclosed |
| US-9585848-B2 | Small molecule xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-03-07 | — | — | US | disclosed |
| US-9585847-B2 | Small molecule xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-03-07 | — | — | US | disclosed |
| US-9585847-B2 | Small molecule xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-03-07 | — | — | US | disclosed |
| US-9580379-B2 | Xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160089342-A1 | METHOD OF INHIBITING XANTHINE OXIDASE ACTIVITY IN A CELL | BAYLOR COLLEGE OF MEDICINE | 2016-03-31 | — | — | US | disclosed |
| CN-1064673-C | New method for preparation of 3,4-dihydroxy-5-nitrobenzaldehyde | ORION YHTYMAE OY (FI) | 2001-04-18 | — | — | CN | disclosed |
| EP-0782559-B1 | NEW METHOD FOR THE PREPARATION OF 3,4-DIHYDROXY-5-NITROBENZALDEHYDE | ORIONYHTYMAE OY (FI) | 1999-01-13 | — | — | EP | disclosed |
| US-5710343-A | Method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde | ORION-YHTYMA OY (FI) | 1998-01-20 | — | — | US | disclosed |
| CN-1164852-A | New preparation method of 3, 4-dihydroxy-5-nitrobenzaldehyde | ORION YHTYMAE OY (FI) | 1997-11-12 | — | — | CN | disclosed |
| EP-0782559-A1 | NEW METHOD FOR THE PREPARATION OF 3,4-DIHYDROXY-5-NITROBENZALDEHYDE | ORIONYHTYMÄ OY (FI) | 1997-07-09 | — | — | EP | disclosed |
| EP-0589948-B1 | METHOD FOR THE PREPARATION OF 3,4-DIHYDROXY-5-NITROBENZALDEHYDE | ORION YHTYMAE OY (FI) | 1996-09-04 | — | — | EP | disclosed |
| WO-1996009274-A1 | NEW METHOD FOR THE PREPARATION OF 3,4-DIHYDROXY-5-NITROBENZALDEHYDE | Orion-Yhtymä Oy (FI) | 1996-03-28 | — | — | WO | disclosed |
| US-5382699-A | Method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde | ORION-YHTYMA OY (FI) | 1995-01-17 | — | — | US | disclosed |
| EP-0589948-A1 | METHOD FOR THE PREPARATION OF 3,4-DIHYDROXY-5-NITROBENZALDEHYDE. | ORION YHTYMAE OY (FI) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993000323-A1 | METHOD FOR THE PREPARATION OF 3,4-DIHYDROXY-5-NITROBENZALDEHYDE | Orion-Yhtymä Oy (FI) | 1993-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160089342-A1 | METHOD OF INHIBITING XANTHINE OXIDASE ACTIVITY IN A CELL | XDH, PNPO, AOX1 | ERN1 1485/4885XDH 1/4885GPR35 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.