Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15177149 | 0.90 | ELOVL1 (0.43) | CXCR2ELOVL1MAOBLMNATDP1 | |
| SCHEMBL15177140 | 0.82 | GPR84 (0.39) | MAOBALDH1A1GPR84 | |
| SCHEMBL16093387 | 0.80 | CXCR2 (0.43) | CXCR2ELOVL1MAOBGRM5CYP11B1 | |
| SCHEMBL28791339 | 0.80 | CXCR2 (0.63) | CXCR2GRM5ALDH1A1TDP1GABRA5 | |
| SCHEMBL510425 | 0.78 | CXCR2 (0.44) | CXCR2ELOVL1MAOBGRM5CYP11B1 | |
| SCHEMBL1712285 | 0.77 | CXCR2 (0.47) | CXCR2ELOVL1MAOBGRM5CYP11B1 | |
| SCHEMBL509327 | 0.76 | MAOB (0.46) | CXCR2MAOBGRM5CYP11B1CYP11B2 | |
| SCHEMBL16093376 | 0.76 | GPR84 (0.40) | ELOVL1MAOBGRM5LMNATDP1 | |
| SCHEMBL510483 | 0.76 | ALDH1A1 (0.55) | CXCR2MAOBGRM5CYP11B1CYP11B2 | |
| SCHEMBL16440939 | 0.76 | MAOB (0.67) | MAOBSENP8SENP7SENP6APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841327-B2 | Heterocycles substituted pyridine derivatives and antifungal agent containing thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-09-23 | — | — | US | disclosed |