Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15177161 | 0.84 | GABRA5 (0.44) | CYP11B1CYP11B2MEN1KMT2ALCK | |
| SCHEMBL509264 | 0.82 | MAOA (0.48) | CYP11B1CYP11B2MEN1KMT2AKLKB1 | |
| SCHEMBL16093384 | 0.81 | SENP8 (0.39) | CYP11B1CYP11B2MEN1KMT2AKLKB1 | |
| SCHEMBL17696415 | 0.80 | MAOB (0.45) | CYP11B1CYP11B2MEN1KMT2ANPC1 | |
| SCHEMBL512665 | 0.80 | MAOA (0.55) | MAOAMAOB | |
| SCHEMBL512664 | 0.80 | MAOA (0.55) | MAOAMAOB | |
| SCHEMBL1680857 | 0.79 | MAOB (0.50) | MEN1KMT2AKLKB1NPC1RAB9A | |
| SCHEMBL608607 | 0.78 | TSHR (0.45) | CYP11B1CYP11B2GRM5LMNATSHR | |
| SCHEMBL13513283 | 0.78 | ALDH1A1 (0.51) | LCKNPC1RAB9ALMNATSHR | |
| SCHEMBL17129497 | 0.77 | IDO1 (0.45) | CYP11B1CYP11B2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841327-B2 | Heterocycles substituted pyridine derivatives and antifungal agent containing thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-09-23 | — | — | US | disclosed |