Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.30 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.30 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095192 | 0.81 | MGLL (0.38) | NPY5RKCNH2MAP3K12MGLLUSP30 | |
| SCHEMBL16095272 | 0.79 | NPY5R (0.35) | NPY5RKCNH2 | |
| SCHEMBL16033875 | 0.74 | NPY5R (0.38) | NPY5RKCNH2USP30 | |
| SCHEMBL16095604 | 0.74 | KDM4C (0.36) | NPY5RKCNH2LRRK2 | |
| SCHEMBL17604548 | 0.71 | NPY5R (0.38) | NPY5RKCNH2USP30 | |
| SCHEMBL16095225 | 0.70 | NPY5R (0.41) | NPY5RKCNH2 | |
| SCHEMBL9792784 | 0.66 | NPY5R (0.45) | NPY5RKCNH2USP30 | |
| SCHEMBL29500425 | 0.66 | NPY5R (0.45) | NPY5RKCNH2USP30 | |
| SCHEMBL16095837 | 0.65 | KDM4C (0.36) | KCNH2 | |
| SCHEMBL29761043 | 0.65 | CDC7 (0.47) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |